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Nosocomial outbreak of SARS-CoV-2 delta variant among vaccinated healthcare workers and immunocompromised patients on a solid-organ transplant unit: Complexities of an epidemiologic and genomic investigation

Published online by Cambridge University Press:  09 September 2022

Jonathan H. Ryder*
Affiliation:
Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska
Trevor C. Van Schooneveld
Affiliation:
Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska
Baha Abdalhamid
Affiliation:
Nebraska Public Health Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska
Macy G. Wood
Affiliation:
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska
Taylor A. Wahlig
Affiliation:
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska
Richard Starlin
Affiliation:
Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska
Gayle Gillett
Affiliation:
Department of Infection Control and Epidemiology, Nebraska Medicine, Omaha, Nebraska
Teresa Balfour
Affiliation:
Nebraska Medicine, Omaha, Nebraska
Libby Pflueger
Affiliation:
Nebraska Medicine, Omaha, Nebraska
Mark E. Rupp
Affiliation:
Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska
*
Author for correspondence: Jonathan Ryder, E-mail: jonathan.ryder@unmc.edu

Abstract

In September 2021, a cluster of 6 patients with nosocomial coronavirus disease 2019 (COVID-19) were identified in a transplant unit. A visitor and 11 healthcare workers also tested positive for severe acute respiratory coronavirus virus 2 (SARS-CoV-2). Genomic sequencing identified 3 separate introductions of SARS-CoV-2 with related transmission among the identified patients and healthcare workers.

Type
Concise Communication
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

PREVIOUS PRESENTATION. Part of the material in this article was presented as an oral abstract at the Society of Hospital Epidemiology of America Annual Meeting 2022 and was published online: Ryder J, Van Schooneveld T, Abdalhamid B, et al. Nosocomial outbreak of δ (delta) variant SARS-CoV-2 on a liver transplant unit: a complex epidemiologic and genomic investigation. Antimicrob Steward Healthc Epidemiol 2022;2:s83–s84.

References

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