Hostname: page-component-8448b6f56d-gtxcr Total loading time: 0 Render date: 2024-04-19T00:33:35.919Z Has data issue: false hasContentIssue false
  • English
  • Français

Fertilistion in sea urchins: how many different molecules are involved in gamete interaction and fusion?

Published online by Cambridge University Press:  26 September 2008

William J. Lennarz
William J. Lennarz*
Affiliation:
Departmnet of Biochemistry and cell Biology, State University of New York at Stony Brook, New York, USA.
*
W.J. Lennarz, Department of Biochemistry and Cell Biology, State University of New York at Strony Brook, Stony Brook, NY 11794-5215, USA. Tel: (516) 632-8560. Fax: (516) 632-8575.
Get access Rights & Permissions [Opens in a new window]

Summary

It has been established that fertilisation in the sea urchin involves binding of acrosome-reacted sperm to an egg cell surface receptor. The structure and function of receptor, as well as the possible involvement of other cell surface molecules in the binding, fusion and activation events, is discussed.

Keywords

BindinEgg surface receptorFertilisation – sea urchinSperm – egg binding
Type
Commentary
Information
Zygote , Volume 2 , Issue 1 , February 1994 , pp. 1 - 4
Copyright
Copyright © Cambridge University Press 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baltz, J.M., Katz, D.F. & Cone, R.A. (1988) Mechanics of sperm-egg interaction at the zona pellucida. Biophys. J. 54, 643–54.Google Scholar
Foltz, K.R. & Lennarz, W.J. (1990). Purification and characterization of an extracellular fragment of the sea urchin egg receptor for sperm. J. Cell Biol. 111, 2951–59.CrossRefGoogle ScholarPubMed
Foltz, K.R. & Lennarz, W.J. (1992). Identification of the sea urchin egg receptor for sperm using an antiserum raised against its extracellular domain. J. Cell Biol. 116, 746–58.CrossRefGoogle ScholarPubMed
Foltz, K.R. & Lennarz, W.J. (1993). The molecular basis of sea urchin gamete interactions at the egg plasma membrane. Dev. Biol. 158, 46–61.CrossRefGoogle ScholarPubMed
Foltz, K.R., Partin, J.S. & Lennarz, W.J., (1993). Sea urchin egg receptor for sperm: sequence similarity of binding domain and hsp70. science. 259, 1421–5.Google Scholar
Glabe, C.G. &Lennarz, W.J. (1979). Species-specific sperm adhesion in sea urchins: a quantitative investigation of bindin-mediated egg agglutination. J. Cell Biol. 83, 595–604Google Scholar
Glabe, C.G. & vacquier, V.D. (1977). Species specific agglutination of eggs by bindin isolated from sea urchin sperm. Nature 267, 836–7CrossRefGoogle ScholarPubMed
Kennedy, L., DeAngelis, P.L. & Glabe, C.G. (1989). Analysis of the membrane-interacting domain of the sea urchin sperm adhesive protein bindin. Biochemistry 28, 9153–8.Google Scholar
Miner, J.E., Gao, B. &Davidson, E.H. (1989). The molecular-biology of bindin. In: The Molecular Biology of Fertilization, ed. H., Schatten & G., SchattenNew York: Academic press pp 73–88.Google Scholar
Moy, G.W. & Vacquier, V.D. (1979). Immunoperoxidase localization of bindin sea urchin fertilization. Curr. Top. Dev. Biol 13, 31–44.CrossRefGoogle Scholar
Ohlendieck, K., Partin, J.S. & Lennarz, W.J. (1994). The biologically active form of the sea urchin egg receptor for sperm is a homo-tetramer. J.cell Biol (submitted).CrossRefGoogle Scholar
Ohlendieck, K., Dhume, S.T., Partin, J.S. & Lennarz, W.J. (1993). The sea urchin receptor for sperm: isolation and characterization of the intact, biologically active receptor. J.Cell. Biol 122, 887–95.CrossRefGoogle ScholarPubMed
Roe, J.L., Farach, H.A., strittmatter, W.J. & Lennarz, W.J. (1988). Evidence for involvement of metalloendoproteases in a step in sea urchin gamete fusio. J.Cell Biol 107, 539–44.Google Scholar
Ruiz-Bravo, N., & Lennarz, W.J. (1986 a). Receptors and membrane interactions during fertilization In: The Molecular Biology of Fertilization ed. H., Schatten & G., Schatten, New York: Academic press 21–36.Google Scholar
Ruiz-Bravo, N.,Earles, D. & Lennarz, W.J. (1986 b). Identification and partial characterization of sperm receptor associated with the newly formed fertilization envelope from sea urchin eggs. Dev. Biol 117, 204–8.CrossRefGoogle ScholarPubMed
Stears, R.L. & Lennarz, W.J. (1993). Mapping of the sperm binding domain on the sea urchin sperm receptor. Mol. Biol. cell 4, 247aGoogle Scholar
Trimmer, J.S. & Vacquier, V.D. (1986). Activation of sea urchin gametes. Annu. Rev. cell Biol. 2, 1–26.CrossRefGoogle ScholarPubMed