Skip to main content Accessibility help
×
Home
Hostname: page-component-55597f9d44-mzfmx Total loading time: 0.415 Render date: 2022-08-15T14:20:57.941Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "useRatesEcommerce": false, "useNewApi": true } hasContentIssue true

Article contents

Potential amplification of early pregnancy signals by ovarian follicular cells in suspension within the Fallopian tube

Published online by Cambridge University Press:  27 November 2003

R.H.F. Hunter
Affiliation:
Faculty of Veterinary Medicine, University of Cambridge, Cambridge, UK Institute for Reproductive Medicine, School of Veterinary Medicine, Hannover, Germany
N. Einer-Jensen
Affiliation:
Departments of Physiology & Pharmacology, University of Southern Denmark, Odense, Denmark

Abstract

That a mammalian embryo might influence the maternal endocrinological and/or immunological systems whilst still in the Fallopian tube has long seemed possible (Fig. 1). Under normal circumstances, the embryo contains a full diploid complement of genetic information and thus the point at issue is just how soon instructions in the genome are expressed for trophic purposes. It could be argued from several points of view that it would be biologically prudent for an embryo to influence the mother whilst still at an early stage of development. Consideration of the extremely intimate apposition of the zona pellucida and the tubal epithelium - perhaps best appreciated in scanning electron micrographs (Fig. 2) - also suggests scope for a mutual exchange of signals. Even so, one of the earliest recorded maternal responses to a developing embryo is the change in permeability of the capillary bed of the uterus that precedes implantation in rodents: this can be demonstrated by the Pontamine blue reaction, a series of bands of dye in the uterine wall corresponding to the location of individual embryos, and is detectable in rats on the fourth day after mating (Psychoyos, 1960, 1973).

Type
Forum
Copyright
2003 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)
12
Cited by

Save article to Kindle

To save this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Potential amplification of early pregnancy signals by ovarian follicular cells in suspension within the Fallopian tube
Available formats
×

Save article to Dropbox

To save this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about saving content to Dropbox.

Potential amplification of early pregnancy signals by ovarian follicular cells in suspension within the Fallopian tube
Available formats
×

Save article to Google Drive

To save this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you used this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about saving content to Google Drive.

Potential amplification of early pregnancy signals by ovarian follicular cells in suspension within the Fallopian tube
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *