Hostname: page-component-77c89778f8-m8s7h Total loading time: 0 Render date: 2024-07-20T21:32:55.592Z Has data issue: false hasContentIssue false
  • English
  • Français

Comparative aspects of Fusarium mycotoxicoses in poultry fed diets containing naturally contaminated grains

Published online by Cambridge University Press:  18 March 2010

G.N. GIRGIS  and
T.K. SMITH
G.N. GIRGIS
Affiliation:
Department of Animal and Poultry Science, University of Guelph, 50 Stone Road East, Building # 70, Guelph, Canada, N1G 2W1
T.K. SMITH*
Affiliation:
Department of Animal and Poultry Science, University of Guelph, 50 Stone Road East, Building # 70, Guelph, Canada, N1G 2W1
*
Corresponding author: tsmith@uoguelph.ca
Get access

Abstract

Fusarium mycotoxins are structurally diverse chemically distinct groups of fungal metabolites which are prevalent globally. Economically important Fusarium mycotoxins include trichothecenes, zearalenone and fumonisins. Deoxynivalenol (DON, vomitoxin), and its acetylated forms, are the most commonly encountered trichothecenes in grains used for poultry feeds. Early experiments, conducted for short periods or using single purified compounds, showed that poultry were resistant to DON. More recent experiments, utilising naturally contaminated grains fed to poultry for extended durations, have shown that combinations of Fusarium mycotoxins pose significant risks to poultry performance and health. Turkeys appear to be more sensitive to Fusarium mycotoxicoses than chickens, while ducks have proven to be the most resistant poultry species. This review discusses various aspects of mycotoxicoses in poultry fed diets containing grains naturally contaminated with Fusarium mycotoxins.

Keywords

Fusarium mycotoxinspoultrynatural contaminationtrichothecenes
Type
Review Article
Information
World's Poultry Science Journal , Volume 66 , Issue 1 , March 2010 , pp. 65 - 86
Copyright
World's Poultry Science Association 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

AWAD, W.A., BÖHM, J., RAZZAZI-FAZELI, E. and ZENTEK, J. (2006) Effects of feeding deoxynivalenol contaminated wheat on growth performance, organ weights and histological parameters of the intestine of broiler chickens. Journal of Animal Physiology and Animal Nutrition 90: 32-37.CrossRefGoogle ScholarPubMed
BERGSJØ, B., HERSTAD, O. and NAFSTAD, I. (1993) Effects of feeding deoxynivalenol-contaminated oats on production performance in White Leghorn hens. British Poultry Science 34: 147-159.CrossRefGoogle ScholarPubMed
BERTHILLER, F., Dall'ASTA, C., SCHUHMACHER, R., LEMMENS, M., ADAM, G. and KRSKA, R. (2005) Masked mycotoxins: determination of a deoxynivalenol glucoside in artificially and naturally contaminated wheat by liquid chromatography-tandem mass spectrometry. Journal of Agricultural and Food Chemistry 53: 3421-3425.CrossRefGoogle ScholarPubMed
BOSTON, S., WOBESER, G. and GILLESPIE, M. (1996) Consumption of deoxynivalenol-contaminated wheat by mallard ducks under experimental conditions. Journal of Wildlife Diseases 32: 17-22.CrossRefGoogle ScholarPubMed
CHOWDHURY, S.R. and SMITH, T.K. (2004) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of laying hens. Poultry Science 83: 1849-1856.CrossRefGoogle ScholarPubMed
CHOWDHURY, S.R. and SMITH, T.K. (2005) Effects of feeding grains naturally contaminated with Fusarium mycotoxins on hepatic fractional protein synthesis rates of laying hens and the efficacy of a polymeric glucomannan mycotoxin adsorbent. Poultry Science 84: 1671-1674.CrossRefGoogle ScholarPubMed
CHOWDHURY, S.R. and SMITH, T.K. (2007) Effects of feed-borne Fusarium mycotoxins on performance, plasma chemistry and hepatic fractional protein synthesis rates of turkeys. Canadian Journal of Animal Science 87: 543-551.CrossRefGoogle Scholar
CHOWDHURY, S.R., SMITH, T.K., BOERMANS, H.J., SEFTON, A.E., DOWNEY, R. and WOODWARD, B. (2005a) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, metabolism, hematology and immunocompetence of ducklings. Poultry Science 84: 1179-1185.CrossRefGoogle ScholarPubMed
CHOWDHURY, S.R., SMITH, T.K., BOERMANS, H.J. and WOODWARD, B. (2005b) Effects of feed-borne Fusarium mycotoxins on hematology and immunology of turkeys. Poultry Science 84: 1698-1706.CrossRefGoogle ScholarPubMed
CHOWDHURY, S.R., SMITH, T.K., BOERMANS, H.J. and WOODWARD, B. (2005c) Effects of feed-borne Fusarium mycotoxins on hematology and immunology of laying hens. Poultry Science, 84: 1841-1850.CrossRefGoogle ScholarPubMed
DÄNICKE, S., MATTHES, S., HALLE, I., UEBERSCHÄR, K.H., DÖLL, S. and VALENTA, H. (2003) Effects of graded levels of Fusarium toxin-contaminated wheat and of a detoxifying agent in broiler diets on performance, nutrient digestibility and blood chemical parameters. British Poultry Science 44: 113-126.CrossRefGoogle ScholarPubMed
DÄNICKE, S., UEBERSCHÄR, K.H., HALLE, I., MATTHES, S., VALENTA, H. and FLACHOWSKY, G. (2002) Effect of addition of a detoxifying agent to laying hen diets containing uncontaminated or Fusarium toxin-contaminated maize on performance of hens and on carryover of zearalenone. Poultry Science 81: 1671-1680.CrossRefGoogle ScholarPubMed
DÄNICKE, S., UEBERSCHÄR, K.H., VALENTA, H., MATTHES, S., MATTHÄUS, K. and HALLE, I. (2004) Effects of graded levels of Fusarium-toxin-contaminated wheat in Pekin duck diets on performance, health and metabolism of deoxynivalenol and zearalenone. British Poultry Science 45: 264-272.CrossRefGoogle ScholarPubMed
DÄNICKE, S., VALENTA, H. and MATTHES, S. (2007a) On the interactions between Fusarium toxin-contaminated wheat and nonstarch polysaccharide hydrolyzing enzymes in diets of broilers on performance, intestinal viscosity, and carryover of deoxynivalenol. Poultry Science 86: 291-298.CrossRefGoogle ScholarPubMed
DÄNICKE, S., VALENTA, H., UEBERSCHÄR, K.H. and MATTHES, S. (2007b) On the interactions between Fusarium toxin-contaminated wheat and non-starch-polysaccharide hydrolysing enzymes in turkey diets on performance, health and carryover of deoxynivalenol and zearalenone. British Poultry Science 48: 39-48.CrossRefGoogle ScholarPubMed
D'MELLO, J.P.F., PORTER, J.K. and PLACINTA, C.M. (1997) Fusarium mycotoxins, in: D'MELLO, J.P.F. (Ed.) Handbook of Plant and Fungal Toxicants, pp. 287-301 (CRC Press, Boca Raton, FL).Google Scholar
EL-BANNA, A.A., HAMILTON, R.M.G., SCOTT, P.M. and TRENHOLM, H.L. (1983) Nontransmission of deoxynivalenol (vomitoxin) to eggs and meat in chickens fed deoxynivalenol-contaminated diets. Journal of Agricultural and Food Chemistry 31: 1381-1384.CrossRefGoogle ScholarPubMed
GIRGIS, G.N., BARTA, J.R., BRASH, M. and SMITH, T.K. (2010) Morphological changes in the intestine of broiler breeder pullets fed diets naturally contaminated with Fusarium mycotoxins with or without coccidial challenge. Avian Diseases 54: in press.CrossRefGoogle ScholarPubMed
GIRGIS, G.N., SHARIF, S., BARTA, J.R., BOERMANS, H.J. and SMITH, T.K. (2008) Immunomodulatory effects of feed-borne Fusarium mycotoxins in chickens infected with coccidia. Experimental Biology and Medicine 233: 1411-1420.CrossRefGoogle ScholarPubMed
GIRISH, C.K. and SMITH, T.K. (2008) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on small intestinal morphology of turkeys. Poultry Science 87: 1075-1082.CrossRefGoogle ScholarPubMed
GIRISH, C.K., MACDONALD, E.J., SCHEININ, M. and SMITH, T.K. (2008a) Effects of feedborne Fusarium mycotoxins on brain neurochemistry of turkeys. Poultry Science 87: 1295-1302.CrossRefGoogle ScholarPubMed
GIRISH, C.K., SMITH, T.K., BOERMANS, H.J. and KARROW, N.A. (2008b) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on performance, hematology, metabolism and immunocompetence of turkeys. Poultry Science 87: 421-432.CrossRefGoogle ScholarPubMed
HAMILTON, R.M.G., THOMPSON, B.K., TRENHOLM, H.L., FISER. P.S., and GREENHALGH, R. (1985a) Effects of feeding White Leghorn hens diets that contain deoxynivalenol (vomitoxin)-contaminated wheat. Poultry Science 64: 1840-1852.CrossRefGoogle ScholarPubMed
HAMILTON, R.M.G., TRENHOLM, H.L., THOMPSON, B.K. and GREENHALGH, R. (1985b) The tolerance of White Leghorn and broiler chicks, and turkey poults to diets that contained deoxynivalenol (vomitoxin)-contaminated wheat. Poultry Science 64: 1840-1852.CrossRefGoogle ScholarPubMed
HARVEY, R.B., KUBENA, L.F., HUFF, W.E., ELISSALDE, M.H., HOLT, P.S., NAQI, S.A. and PHILLIPS, T.D. (1988) Hematologic and immunologic status of chicks fed deoxynivalenol (DON)-contaminated diets. Proceedings of the 39th North Central Avian Disease Conference, pp. 48-50.Google Scholar
HARVEY, R.B., KUBENA, L.F., HUFF, W.E., ELISSALDE, M.H. and PHILLIPS, T.D. (1991) Hematologic and immunologic toxicity of deoxynivalenol (DON)-contaminated diets to growing chickens. Bulletin of Environmental Contamination and Toxicology 46: 410-416.CrossRefGoogle ScholarPubMed
HARVEY, R.B., KUBENA, L.F., ROTTINGHAUS, G.E., TURK, J.R., CASPER, H.H. and BUCKLEY, S.A. (1997) Moniliformin from Fusarium fujikuroi culture material and deoxynivalenol from naturally contaminated wheat incorporated into diets of broiler chicks. Avian Diseases 41: 957-963.CrossRefGoogle ScholarPubMed
HUFF, W.E., DOERR, J.A., HAMILTON, P.B. and VESONDER, R.F. (1981) Acute toxicity of vomitoxin (deoxynivalenol) in broiler chickens. Poultry Science 60: 1412-1414.CrossRefGoogle ScholarPubMed
HUFF, W.E., KUBENA, L.F., HARVEY, R.B., HAGLER, W.M.JR., SWANSON, S.P., PHILLIPS, T.D. and CREGER, C.R. (1986) Individual and combined effects of aflatoxin and deoxynivalenol (DON, vomitoxin) in broiler chickens. Poultry Science 65: 1291-1298.CrossRefGoogle ScholarPubMed
HULAN, H.W. and PROUDFOOT, F.G. (1982) Effects of feeding vomitoxin contaminated wheat on the performance of broiler chickens. Poultry Science 61: 1653-1659.CrossRefGoogle ScholarPubMed
KESHAVARZ, K. (1993) Corn contaminated with deoxynivalenol: effects on performance of poultry. Journal of Applied Poultry Research 2: 43-50.CrossRefGoogle Scholar
KHAJARERN, J.M., KHAJARERN, S., MOON, T.H. AND LEE and J.H., (2003) Effects of dietary supplementation of fermented chitin-chitosan (FERMKIT) on toxicity of mycotoxin in ducks. Asian-Australasian Journal of Animal Science 16: 706-713.CrossRefGoogle Scholar
KONJEVIĆ, D., SREBOČAN, E., GUDAN, A., LOJKIĆ, I., SEVERIN, K. and SOKOLOVIĆ, M. (2004) A pathological condition possibly caused by spontaneous trichothecene poisoning in Brahma poultry: first report. Avian Pathology 33: 377-380.CrossRefGoogle ScholarPubMed
KUBENA, L.F. and HARVEY, R.B. (1988) Research note: Response of growing Leghorn chicks to deoxynivalenol-contaminated wheat. Poultry Science 67: 1778-1780.CrossRefGoogle Scholar
KUBENA, L.F., EDRINGTON, T.S., HARVEY, R.B., BUCKLEY, S.A., PHILLIPS, T.D., ROTTINGHAUS, G.E. and CASPER, H.H. (1997) Individual and combined effects of fumonisin B1 present in Fusarium moniliforme culture material and T-2 toxin or deoxynivalenol in broiler chicks. Poultry Science 76: 1239-1247.CrossRefGoogle ScholarPubMed
KUBENA, L.F., HARVEY, R.B., CORRIER, D.E., HUFF, W.E. and PHILLIPS, T.D. (1987a) Effects of feeding deoxynivalenol (DON, vomitoxin)-contaminated wheat to female while Leghorn chickens from day old through egg production. Poultry Science 66: 1612-1618.CrossRefGoogle ScholarPubMed
KUBENA, L.F., HARVEY, R.B., PHILLIPS, T.D., HOLMAN, G.M. and CREGER, C.R. (1987b) Effects of feeding mature While Leghorn hens diets that contain deoxynivalenol (vomitoxin). Poultry Science 66: 55-58.CrossRefGoogle ScholarPubMed
KUBENA, L.F., HUFF, W.E., HARVEY, R.B., CORRIER, D.E., PHILLIPS, T.D. and CREGER, C.R. (1988) Influence of ochratoxin A and deoxynivalenol on growing broiler chicks. Poultry Science 67: 253-260.CrossRefGoogle ScholarPubMed
KUBENA, L.F., HUFF, W.E., HARVEY, R.B., PHILLIPS, T.D. and ROTTINGHAUS, G.E. (1989) Individual and combined toxicity of deoxynivalenol and T-2 toxin in broiler chicks. Poultry Science 68: 622-626.CrossRefGoogle ScholarPubMed
KUBENA, L.F., SWANSON, S.P., HARVEY, R.B., FLETCHER, O.J., ROWE, L.D. and PHILLIPS, T.D. (1985) Effects of feeding deoxynivalenol (vomitoxin)-contaminated wheat to growing chicks. Poultry Science 64: 1649-1655.CrossRefGoogle Scholar
LUN, A.K., YOUNG, L.G., MORAN, E.T.. JR, HUNTER, D.B. and RODRIGUEZ, J.P. (1986) Effects of feeding hens a high level of vomitoxin-contaminated corn on performance and tissue residues. Poultry Science 65: 1095-1099.CrossRefGoogle Scholar
MARASAS, W.F.O. (2001) Discovery and occurrence of the fumonisins: a historical perspective. Environmental Health Perspectives 109: 239-243.Google ScholarPubMed
MORAN, E.T. JR, FERKET, P.R. and LUN, A.K. (1987) Impact of high dietary vomitoxin on yolk yield and embryonic mortality. Poultry Science 66: 977-982.CrossRefGoogle ScholarPubMed
MORAN, E.T. JR, HUNTER, B., FERKET, P., YOUNG, L.G. and MCGIRR, L.G. (1982) High tolerance of broilers to vomitoxin from corn infected with Fusarium graminearum. Poultry Science 61: 1828-1831.CrossRefGoogle ScholarPubMed
MOSS, M.O. and THRANE, U. (2004) Fusarium taxonomy with relation to trichothecene formation. Toxicology Letters 153: 23-28.CrossRefGoogle ScholarPubMed
PETTERSSON, H., HEDMAN, R., ENGSTRÖM, B., ELWINGER, K. and FOSSUM, O. (1995) Nivalenol in Swedish cereals – occurrence, production and toxicity towards chickens. Food additives and Contaminants 12: 373-376.CrossRefGoogle ScholarPubMed
PLACINTA, C.M., D'MELLO, J.P.F. and MACDONALD, A.M.C. (1999) A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Animal Feed Science and Technology 78: 21-37.CrossRefGoogle Scholar
SCIENTIFIC COMMITTEE ON FOOD (SCF), and EUROPEAN COMMISSON, (1999) Opinion on Fusarium toxins. Part 1: Deoxynivalenol (DON).Google Scholar
SCHNEWEIS, I., MEYER, K., ENGELHARDT, G. and BAUER, J. (2002) Occurrence of zearalenone-4-β-D-glucopyranoside in wheat. Journal of Agricultural and Food Chemistry 50: 1736-1738.CrossRefGoogle ScholarPubMed
SMITH, T.K., MCMILLAN, E.G. and CASTILLO, J.B. (1997) Effect of feeding blends of Fusarium mycotoxin-contaminated grains containing deoxynivalenol and fusaric acid on growth and feed consumption of immature swine. Journal of Animal Science 75: 2184-2191.CrossRefGoogle ScholarPubMed
SWAMY, H.V.L.N., SMITH, T.K., COTTER, P.F., BOERMANS, H.J. and SEFTON A.E., (2002) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on production and metabolism of broilers. Poultry Science 81: 966-975.CrossRefGoogle ScholarPubMed
SWAMY, H.V.L.N., SMITH, T.K., KARROW, N.A. and BOERMANS, H.J. (2004a) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on growth and immunological parameters of broiler chickens. Poultry Science 83: 533-543.CrossRefGoogle ScholarPubMed
SWAMY, H.V.L.N., SMITH, T.K. and MACDONALD, E.J. (2004b) Effects of feeding blends of grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of starter pigs and broiler chickens. Journal of Animal Science 82: 2131-2139.CrossRefGoogle ScholarPubMed
SYPECKA, Z., KELLY, M. and BRERETON, P. (2004) Deoxynivalenol and zearalenone residues in eggs of laying hens fed with a naturally contaminated diet: effects on egg production and estimation of transmission rates from feed to eggs. Journal of Agricultural and Food Chemistry 52: 5463-5471.CrossRefGoogle ScholarPubMed
VALENTA, H. and DÄNICKE, S. (2005) Study on the transmission of deoxynivalenol and de-epoxy-deoxynivalenol into eggs of laying hens using a high-performance liquid chromatography-ultraviolet method with clean-up by immunoaffinity columns. Molecular Nutrition and Food Research 49: 779-785.CrossRefGoogle Scholar
YEGANI, M., CHOWDHURY, S.R., OINAS, N., MACDONALD, E.J. and SMITH, T.K. (2006a) Effects of feeding grains naturally contaminated with Fusarium mycotoxins on brain regional neurochemistry of laying hens, turkey poults and broiler breeder hens. Poultry Science 85: 2117-2123.CrossRefGoogle ScholarPubMed
YEGANI, M., SMITH, T.K., LEESON, S. and BOERMANS H.J., (2006b) Effects of feeding grains naturally contaminated with Fusarium mycotoxins on performance and metabolism of broiler breeder. Poultry Science 85: 1541-1549.CrossRefGoogle Scholar