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Topography of long- and middle-wavelength sensitive cone opsin gene expression in human and Old World monkey retina

Published online by Cambridge University Press:  06 September 2006

MAUREEN NEITZ ,
SHAWN D. BALDING ,
CARRIE MCMAHON ,
STACY A. SJOBERG  and
JAY NEITZ
MAUREEN NEITZ
Affiliation:
Department of Ophthalmology, and Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin
SHAWN D. BALDING
Affiliation:
Department of Ophthalmology, and Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin
CARRIE MCMAHON
Affiliation:
Department of Ophthalmology, and Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin
STACY A. SJOBERG
Affiliation:
Department of Ophthalmology, and Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin
JAY NEITZ
Affiliation:
Department of Ophthalmology, and Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin
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Abstract

The topographical distributions of the relative ratio of long- (L) and middle- (M) wavelength sensitive cone opsin messenger RNA (mRNA) in human and baboon retinas were mapped using real-time polymerase chain reaction. The L:M mRNA ratio increased in a central-to-peripheral gradient in both species, being quite pronounced for humans.

Keywords

molecular genetics of color vision; cone photopigmentscone topographycone photopigment gene expressionreal time quantitative PCR
Type
GENETICS
Information
Visual Neuroscience , Volume 23 , Issue 3-4 , May 2006 , pp. 379 - 385
Copyright
© 2006 Cambridge University Press

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