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Failure to Obtain Reliable Retrospective Determination of Chorion Type Using Parent Information: Confirmation with French Data

Published online by Cambridge University Press:  21 February 2012

Michéle Carlier  and
Elisabeth Spitz
Michéle Carlier*
Affiliation:
Genetics, Neurogenetics and Behavior, CNRS, France; PsyCLÉ (EA3273), University of Provence, Aix-en-Provence, France. mcarlier@up.univ-aix.fr
Elisabeth Spitz
Affiliation:
Genetics, Neurogenetics and Behavior, CNRS, France; Laboratory of Psychology (EA3477), University of Metz, Saulcy Island, Metz, France.
*
*Address for correspondence: M. Carlier, Laboratory PsyCLÉ (EA3273), Department of Psychology, 29 Avenue Robert Schuman, 13100 Aix-en-Provence, France.

Abstract

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Following the Derom et al. paper recently published in Twin Research (2003, 6, 19–21), we investigated our French sample, studying the retrospective validity of information given by parents to determine the chorion type of their monozygotic twins. The sample included 44 MZ pairs of known chorion type. Chorion type was established by a pathologist specialising in the study of placenta and zygosity diagnosis using molecular genetic techniques. Results show that of the parents who had information, there was a high level of uncertainty of the chorion type. It therefore seems impossible to obtain valid retrospective determination from parents and the only solution is to have accurate information in the birth records.

Type
Articles
Information
Twin Research and Human Genetics , Volume 7 , Issue 1 , 01 February 2004 , pp. 13 - 15
Copyright
Copyright © Cambridge University Press 2004