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Nuclear Magnetic Resonance (NMR) II. Imaging in Dementia

Published online by Cambridge University Press:  29 January 2018

J. A. O. Besson*
Affiliation:
Department of Mental Health, University of Aberdeen
F. M. Corrigan
Affiliation:
Department of Mental Health, University of Aberdeen
E. Iljon Foreman
Affiliation:
Department of Mental Health, University of Aberdeen
L. M. Eastwood
Affiliation:
Department of Biomedical Physics & Bioengineering, University of Aberdeen. Now at M & D Technology Ltd., Whitemyres Avenue, Aberdeen
F. W. Smith
Affiliation:
Aberdeen Royal Infirmary
G. W. Ashcroft
Affiliation:
University of Aberdeen
*
Correspondence

Summary

Proton NMR imaging of the brain is rapidly becoming established as a useful investigative tool in medicine. This paper examines the usefulness of the NMR parameters—spin-lattice relaxation time (T1) and proton density (PD)—in differentiating groups of patients with senile dementia of Alzheimer type (SDAT) and multi-infarct dementia (MID) from each other, and from elderly controls. T1 values increase with severity of dementia. NMR parameters may also be of use in localising regions of brain damage.

Type
Research Article
Copyright
Copyright © 1985 The Royal College of Psychiatrists 

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