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Normothymotics, “Mood-Normalizers”

Are Lithium and the Imipramine Drugs Specific for Affective Disorders?

Published online by Cambridge University Press:  29 January 2018

Mogens Schou
Mogens Schou*
Affiliation:
Neurochemical and Psychopharmacological Research Unit, Institute of Psychiatry, Risskov, Denmark
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Extract

The action of almost all drugs used so far in psychiatric pharmacotherapy has been directed against psychopathological symptoms or syndromes and not against mental diseases as such, the nosological entities defined by classical clinical psychiatry. In this paper the attention will be drawn towards a different type of drug: compounds with an action specific to a disease rather than to a symptom, and evidence will be presented for the existence within this class of a group that is characterized by being active against affective disorders (manic-depressive psychosis). Normothymotics, “mood-normalizers”, is proposed as a collective name for drugs belonging to this group.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 109 , Issue 463 , November 1963 , pp. 803 - 809
Copyright
Copyright © Royal College of Psychiatrists, 1963 

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