Hostname: page-component-84b7d79bbc-4hvwz Total loading time: 0 Render date: 2024-07-29T03:10:21.512Z Has data issue: false hasContentIssue false
  • English
  • Français

Fowkes et al's “Serum Cholesterol, Triglycerides, and Aggression in the General Population”

Published online by Cambridge University Press:  02 January 2018

Alyson J. Bond
Alyson J. Bond*
Affiliation:
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF
Get access Rights & Permissions [Opens in a new window]

Abstract

“A higher than expected number of violent deaths and suicides in coronary prevention trials has provoked interest in the possibility that low serum cholesterol concentrations are associated in the general population with personality characteristics predisposing to aggressive and suicidal behaviour. We have investigated this possibility in the Edinburgh Artery Study. We measured serum lipid concentrations in blood samples taken from fasting subjects and assessed personality characteristics on the Bedford Foulds Personality Deviance Scales in a random sample of 1592 men and women aged 55–74 years, selected from age-sex registers of ten general practices in Edinburgh. Serum cholesterol concentration was not significantly associated with aggression in men, but it was associated in multivariate analysis (though not univariate analysis) with denigratory attitudes towards others among women. However, serum triglyceride concentration was related, especially in men, to hostile acts (r = 0.13, P < 0.001) and domineering attitude (r = 0.12, P < 0.001) independently of age, total and HDL cholesterol, cigarette smoking, and alcohol consumption. Subjects taking part in prevention trials have higher triglyceride concentrations than the general population and the relation between serum triglyceride concentration and aggression merits further investigation.”

Type
The Current Literature
Information
The British Journal of Psychiatry , Volume 163 , Issue 5 , November 1993 , pp. 666 - 668
Copyright
Copyright © Royal College of Psychiatrists, 1993 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

After, A., van Praag, H. M., Plutchik, R., et al (1990) Interrelationships among anxiety, aggression, impulsivity, and mood: a serotonergically linked cluster? Psychiatry Research, 32, 191–199.Google Scholar
Bedford, A. & Foulds, G. A. (1978) Personality Deviance Scale (manual). Windsor: National Foundation for Educational Research.Google Scholar
Coccaro, E. F. (1989) Central serotonin and impulsive aggression. British Journal of Psychiatry, 155 (suppl. 8), 52–62.CrossRefGoogle Scholar
Davey Smith, G., Shipley, M. J., Marmot, M. G., et al (1990) Lowering cholesterol concentrations and mortality. British Medical Journal, 301, 552.Google Scholar
Fowkes, F. G. R., Leng, G. C., Donnan, P. T., et al (1992) Serum cholesterol, triglycerides, and aggression in the general population. Lancet, 340, 995–998.CrossRefGoogle ScholarPubMed
Fredrikson, M. & Blumenthal, J. A. (1992) Serum lipids, neuroendocrine and cardiovascular responses to stress in healthy type A men. Biological Psychiatry, 34, 45–58.CrossRefGoogle ScholarPubMed
Harlan, W. R. Jr, Oberman, A., Mitchell, R. E., et al (1967) Constitutional and environmental factors related to serum lipid and lipoprotein levels. Annals of Internal Medicine, 66, 540–555.Google Scholar
Hecker, M. H. L., Chesney, M. A., Black, G. W., et al (1988) Coronary-prone behaviors in the Western Collaborative Group. Psychosomatic Medicine, 50, 153–164.Google Scholar
Morgan, R. E., Palinkas, L. A., Barrett-Connor, E. L., et al (1993) Plasma cholesterol and depressive symptoms in older men. Lancet, 341, 75–79.Google Scholar
Niaura, R., Stoney, C. M. & Herbert, P. N. (1992a) Lipids in psychological research: the last decade. Biological Psychology, 34, 1–43.Google Scholar
Niaura, R., Herbert, P., McMahon, M., et al (1992b) Repressive coping and blood lipids in men and women. Psychosomatic Medicine, 54, 698–706.Google Scholar
Rochet, T.H., Kopp, N., Vedrinne, J., et al (1992) Benzodiazepine binding sites and their modulators in hippocampus of violent suicide victims. Biological Psychiatry, 32, 922–931.Google Scholar
Roy, A., Adinoff, B., & Linnoila, M., et al (1988) Acting out hostility in normal volunteers: negative correlation with levels of 5-HIAA in cerebrospinal fluid. Psychiatry Research, 24, 187–194.CrossRefGoogle ScholarPubMed
Trevisan, M., Celentano, E., Meucci, C., et al (1986) Short-term effect of natural disasters on coronary heart disease risk factors. Arteriosclerosis, 6, 491–494.Google Scholar
Virkkunen, M., Nuutila, A., Goodwin, F. K., et al (1987) Cerebrospinal fluid metabolite in male arsonists. Archives of General Psychiatry, 44, 241–247.CrossRefGoogle ScholarPubMed
Weidner, G., Connor, S. L., Hollis, J. F., et al (1992) Improvements in hostility and depression in relation to dietary change and cholesterol lowering. Annals of Internal Medicine, 117, 820–823.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.