The European Space Agency (ESA) has selected Rosetta as the next cornerstone mission, to be launched in 2003. The goal is to perfom one or more fly-bys to main belt asteroids, followed by a rendez-vous with an active comet. Advanced in situ analysis, both in the coma and on the surfaces of the nucleus, will be possible, as well as monitoring by remote sensing instruments of the nucleus and of the inner coma for a time span of more than one year, until perihelion. This paper outlines the scientific and technological choices done in the definition of the mission.