Interest in the investigation of male erectile dysfunction and male factor infertility has risen in recent years, due in part to the increased sophistication and high profile of new treatments associated with these conditions. The assessment and management of men presenting with erectile or fertility problems are usually achieved by collaboration between urology and other specialties. A radiologist is often a vital member of this multidisciplinary team. This article will review the imaging modalities currently available and discuss their current role in the investigation of these two key areas of andrology.