Hostname: page-component-848d4c4894-sjtt6 Total loading time: 0 Render date: 2024-06-24T12:29:17.934Z Has data issue: false hasContentIssue false
  • English
  • Français

Tritium in saliva measurements usedfor monitoring of exposed workers

Published online by Cambridge University Press:  14 December 2006

J.P. Le Goff ,
C. Roullet ,
S. Distinguin ,
P. Mangin  and
F. Briot
J.P. Le Goff
Affiliation:
CEA, Service de Santé au Travail, Centre de Valduc/CEA/DAM, 21120 Is-sur-Tille, France
C. Roullet
Affiliation:
CEA, Service de Santé au Travail, Centre de Valduc/CEA/DAM, 21120 Is-sur-Tille, France
S. Distinguin
Affiliation:
CEA, Laboratoire d’Analyses de Biologie Médicale, Centre de Valduc/CEA/DAM, 21120 Is-sur-Tille, France
P. Mangin
Affiliation:
CEA, Laboratoire d’Analyses de Biologie Médicale, Centre de Valduc/CEA/DAM, 21120 Is-sur-Tille, France
F. Briot
Affiliation:
CEA, Laboratoire d’Analyses de Biologie Médicale, Centre de Valduc/CEA/DAM, 21120 Is-sur-Tille, France
Get access

Abstract

Simultaneous measurement of tritium in urine and saliva in exposed workers reveals differences in the kinetic fate of this radioelement in these two bodily fluids. During two years, four cases of accidental exposure, affecting seven workers, were used for these bioassays. Since the concentration of tritium increases much faster in saliva than in urine, a ratio estimated at 1 to 30 at about 30 minutes after contamination occurs, it is possible to consider saliva assay as an alternative to urine assay, which is more common practice today.

Keywords

tritiumtritiated watersalivainternal contaminationbioassay
Type
Research Article
Information
Radioprotection , Volume 41 , Issue 4 , October 2006 , pp. 463 - 469
Copyright
© EDP Sciences, 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Balanov, M.I., Dolgirev, E.I., Likhtarev, I.A. (1974) Exchange kinetics and dosimerty of tritium oxyde in man for different routes of administration, Health Phys. 27, 367-375. CrossRef
Coppen, A.J., Gibbons, J.L. (1960) Salive-Serum Ratios of Tritium after the Administration of Tritiated Water, Nature 186, 724-725. CrossRef
Gardner, J.W., Gutmann, F.D. (2002) Fatal Water Intoxication of an Army Trainee during Urine Drug Testing, Milit. Med. 167, 435-437.
Hesp, R., Smith, T., Veall, N. (1982) The use of saliva samples to determine total body water by tritium dilution, Clin. Phys. Physiol. Meas. 3, 155-157. CrossRef
ICRP Publication 23 (1975) Reference Man: Anatomical, Physical and Metabolic Characteristics. Pergamon Press, Oxford.
ICRP Publication 56 (1989) Age-dependent Doses to Members of the Public from Intake of Radionuclides: Part 1, Ann. ICRP 20(2).