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Treating depression with a smartphone-delivered self-help cognitive behavioral therapy for insomnia: a parallel-group randomized controlled trial

Published online by Cambridge University Press:  23 August 2021

Christian S. Chan*
Affiliation:
The University of Hong Kong, Hong Kong
Christy Y. F. Wong
Affiliation:
The University of Hong Kong, Hong Kong
Branda Y. M. Yu
Affiliation:
The University of Hong Kong, Hong Kong
Victoria K. Y. Hui
Affiliation:
The University of Hong Kong, Hong Kong
Fiona Y. Y. Ho
Affiliation:
Chinese University of Hong Kong, Hong Kong
Pim Cuijpers
Affiliation:
Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
*
Author for correspondence: Christian S. Chan, E-mail: shaunlyn@hku.hk

Abstract

Background

Despite its efficacy in treating comorbid insomnia and depression, cognitive behavioral therapy for insomnia (CBT-I) is limited in its accessibility and, in many countries, cultural compatibility. Smartphone-based treatment is a low-cost, convenient alternative modality. This study evaluated a self-help smartphone-based CBT-I in alleviating major depression and insomnia.

Methods

A parallel-group randomized, waitlist-controlled trial was conducted with 320 adults with major depression and insomnia. Participants were randomized to receive either a 6-week CBT-I via a smartphone application, proACT-S, or waitlist condition. The primary outcomes included depression severity, insomnia severity, and sleep quality. The secondary outcomes included anxiety severity, subjective health, and acceptability of treatment. Assessments were administered at baseline, post-intervention (week 6) follow-up, and week 12 follow-up. The waitlist group received treatment after the week 6 follow-up.

Results

Intention to treat analysis was conducted with multilevel modeling. In all but one model, the interaction between treatment condition and time at week 6 follow-up was significant. Compared with the waitlist group, the treatment group had lower levels of depression [Center for Epidemiologic Studies Depression Scale (CES-D): Cohen's d = 0.86, 95% CI (−10.11 to −5.37)], insomnia [Insomnia Severity Index (ISI): Cohen's d = 1.00, 95% CI (−5.93 to −3.53)], and anxiety [Hospital Anxiety and Depression Scale – Anxiety subscale (HADS-A): Cohen's d = 0.83, 95% CI (−3.75 to −1.96)]. They also had better sleep quality [Pittsburgh Sleep Quality Index (PSQI): Cohen's d = 0.91, 95% CI (−3.34 to −1.83)]. No differences across any measures were found at week 12, after the waitlist control group received the treatment.

Conclusion

proACT-S is an efficacious sleep-focused self-help treatment for major depression and insomnia.

Trial registration

ClinicalTrials.gov, NCT04228146. Retrospectively registered on 14 January 2020. https://clinicaltrials.gov/ct2/show/NCT04228146

Type
Original Article
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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References

American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Arlington, VA: Author. doi: 10.1176/appi.books.9780890425596.Google Scholar
Census and Statistics Department (2017). Usage of information technology and the Internet by Hong Kong resident: 2000 to 2016. Available at: https://www.statistics.gov.hk/pub/B71711FB2017XXXXB0100.pdf.Google Scholar
Hospital Authority (2019). Waiting time for stable new case booking at specialist out-patient clinics. Retrieved October 09 from https://www.ha.org.hk/haho/ho/sopc/dw_wait_ls_eng.pdf.Google Scholar
Alaoui, S. E., Ljótsson, B., Hedman, E., Svanborg, C., Kaldo, V., & Lindefors, N. (2016). Predicting outcome in internet-based cognitive behaviour therapy for major depression: A large cohort study of adult patients in routine psychiatric care. PLoS ONE, 11(9), e0161191.CrossRefGoogle ScholarPubMed
Baddeley, J. L., & Gros, D. F. (2013). Cognitive behavioral therapy for insomnia as a preparatory treatment for exposure therapy for posttraumatic stress disorder. American Journal of Psychotherapy, 67(2), 203214.CrossRefGoogle ScholarPubMed
Ballesio, A., Aquino, M. R. J. V., Feige, B., Johann, A. F., Kyle, S. D., Spiegelhalder, K., … Baglioni, C. (2018). The effectiveness of behavioural and cognitive behavioural therapies for insomnia on depressive and fatigue symptoms: A systematic review and network meta-analysis. Sleep Medicine Reviews, 37, 114129.CrossRefGoogle ScholarPubMed
Bastien, C. H., Vallières, A., & Morin, C. M. (2001). Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Medicine, 2(4), 297307.CrossRefGoogle ScholarPubMed
Beck, A. T., Steer, R. A., Ball, R., & Ranieri, W. (1996). Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. Journal of Personality Assessment, 67(3), 588597. https://doi.org/10.1207/s15327752jpa6703_13.CrossRefGoogle Scholar
Bei, B., Asarnow, L. D., Krystal, A., Edinger, J. D., Buysse, D. J., & Manber, R. (2018). Treating insomnia in depression: Insomnia related factors predict long-term depression trajectories. Journal of Consulting and Clinical Psychology, 86(3), 282293.CrossRefGoogle ScholarPubMed
Ben-Zeev, D., Brenner, C. J., Begale, M., Duffecy, J., Mohr, D. C., & Mueser, K. T. (2014). Feasibility, acceptability, and preliminary efficacy of a smartphone intervention for schizophrenia. Schizophrenia Bulletin, 40(6), 12441253.CrossRefGoogle ScholarPubMed
Bhar, S. S., Gelfand, L. A., Schmid, S. P., Gallop, R., DeRubeis, R. J., Hollon, S. D., … Beck, A. T. (2008). Sequence of improvement in depressive symptoms across cognitive therapy and pharmacotherapy. Journal of Affective Disorders, 110(1–2), 161166.CrossRefGoogle ScholarPubMed
Blom, K., Jernelöv, S., Rück, C., Lindefors, N., & Kaldo, V. (2017). Three-year follow-up comparing cognitive behavioral therapy for depression to cognitive behavioral therapy for insomnia, for patients with both diagnoses. Sleep, 40(8), zsx108. doi: 10.1093/sleep/zsx108CrossRefGoogle ScholarPubMed
Blom, K., Tillgren, H. T., Wiklund, T., Danlycke, E., Forssén, M., Söderström, A., … Kaldo, V. (2015). Internet-vs. group-delivered cognitive behavior therapy for insomnia: A randomized controlled non-inferiority trial. Behaviour Research and Therapy, 70, 4755.CrossRefGoogle ScholarPubMed
Buysse, D. J., Reynolds, C. F. 3rd, Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989). The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2), 193213.CrossRefGoogle ScholarPubMed
Campion, J., Javed, A., Sartorius, N., & Marmot, M. (2020). Addressing the public mental health challenge of COVID-19. The Lancet. Psychiatry, 7(8), 657659.CrossRefGoogle ScholarPubMed
Chakraborty, H., & Gu, H.. (2009). A Mixed Model Approach for Intent-to-Treat Analysis in Longitudinal Clinical Trials with Missing Values. RTI Press publication No. MR-0009-0903. Research Triangle Park, NC: RTI International.Google Scholar
Chakravorty, S., Morales, K. H., Arnedt, J. T., Perlis, M. L., Oslin, D. W., Findley, J. C., & Kranzler, H. R. (2019). Cognitive behavioral therapy for insomnia in alcohol-dependent veterans: A randomized, controlled pilot study. Alcoholism: Clinical and Experimental Research, 43(6), 12441253.Google ScholarPubMed
Chan, C. S., Poon, C. Y. S., Leung, J. C. Y., Lau, K. N. T., & Lau, E. Y. Y. (2018). Delayed school start time is associated with better sleep, daytime functioning, and life satisfaction in residential high-school students. Journal of Adolescence, 66, 4954.CrossRefGoogle ScholarPubMed
Chan, W. C., Wong, C. S. M., Chen, E. Y. H., Ng, R. M. K., Hung, S. F., Cheung, E. F. C., … Lam, L. C. W. (2017). Validation of the Chinese version of the Revised Clinical Interview Schedule: Findings from Hong Kong Mental Morbidity Survey. East Asian Archives of Psychiatry, 27, 310.Google ScholarPubMed
Chin, W. Y., Chan, K. T. Y., Lam, C. L. K., Lam, T. P., & Wan, E. Y. F. (2015). Help-seeking intentions and subsequent 12-month mental health service use in Chinese primary care patients with depressive symptoms. BMJ Open, 5(1), e006730. doi: 10.1136/bmjopen-2014-006730CrossRefGoogle ScholarPubMed
Christensen, H., Batterham, P. J., Gosling, J. A., Ritterband, L. M., Griffiths, K. M., Thorndike, F. P., … Mackinnon, A. J. (2016). Effectiveness of an online insomnia program (SHUTi) for prevention of depressive episodes (the GoodNight Study): A randomised controlled trial. The Lancet. Psychiatry, 3(4), 333341.CrossRefGoogle Scholar
Chung, K. F., & Tang, M. K. (2006). Subjective sleep disturbance and its correlates in middle-aged Hong Kong Chinese women. Maturitas, 53(4), 396404.CrossRefGoogle ScholarPubMed
Chung, K. F., Tse, S., Lee, C. T., Wong, M. M. C., & Chan, W. M. (2019). Experience of stigma among mental health service users in Hong Kong: Are there changes between 2001 and 2017? International Journal of Social Psychiatry, 65(1), 6472.CrossRefGoogle Scholar
Chung, K. F., Yeung, W. F., Ho, Y. Y., Ho, L. M., Yung, K. P., Yu, Y. M., & Kwok, C. W. (2014). Validity and reliability of the Brief Insomnia Questionnaire in the general population in Hong Kong. Journal of Psychosomatic Research, 76(5), 374379. doi: 10.1016/j.jpsychores.2014.03.002CrossRefGoogle ScholarPubMed
Corrigan, P. W., Druss, B. G., & Perlick, D. A. (2014). The impact of mental illness stigma on seeking and participating in mental health care. Psychological Science in the Public Interest, 15(2), 3770.CrossRefGoogle ScholarPubMed
Cuijpers, P., Noma, H., Karyotaki, E., Cipriani, A., & Furukawa, T. A. (2019). Effectiveness and acceptability of cognitive behavior therapy delivery formats in adults with depression: A network meta-analysis. JAMA Psychiatry, 76(7), 700707.CrossRefGoogle ScholarPubMed
Cunningham, J. E. A., & Shapiro, C. M. (2018). Cognitive behavioural therapy for insomnia (CBT-I) to treat depression: A systematic review. Journal of Psychosomatic Research, 106, 112.CrossRefGoogle ScholarPubMed
Devilly, G. J., & Borkovec, T. D. (2000). Psychometric properties of the credibility/expectancy questionnaire. Journal of Behavior Therapy and Experimental Psychiatry, 31(2), 7386.CrossRefGoogle ScholarPubMed
Economides, M., Ranta, K., Nazander, A., Hilgert, O., Goldin, P. R., Raevuori, A., & Forman-Hoffman, V. (2019). Long-term outcomes of a therapist-supported, smartphone-based intervention for elevated symptoms of depression and anxiety: Quasiexperimental, pre-postintervention study. Jmir Mhealth and Uhealth, 7(8), e14284.CrossRefGoogle ScholarPubMed
Espie, C. A., Emsley, R., Kyle, S. D., Gordon, C., Drake, C. L., Siriwardena, A. N., … Luik, A. I. (2019). Effect of digital cognitive behavioral therapy for insomnia on health, psychological well-being, and sleep-related quality of life: A randomized clinical trial. JAMA Psychiatry, 76(1), 2130.CrossRefGoogle ScholarPubMed
Fang, H., Tu, S., Sheng, J. F., & Shao, A. (2019). Depression in sleep disturbance: A review on a bidirectional relationship, mechanisms and treatment. Journal of Cellular and Molecular Medicine, 23(4), 23242332.CrossRefGoogle ScholarPubMed
Feng, G. Y., Han, M., Li, X., Geng, L., & Miao, Y. C. (2020). The clinical effectiveness of cognitive behavioral therapy for patients with insomnia and depression: A systematic review and meta-analysis. Evidence-Based Complementary and Alternative Medicine, 2020, 8071821.CrossRefGoogle ScholarPubMed
Firth, J., Torous, J., Nicholas, J., Carney, R., Pratap, A., Rosenbaum, S., & Sarris, J. (2017a). The efficacy of smartphone-based mental health interventions for depressive symptoms: A meta-analysis of randomized controlled trials. World Psychiatry, 16(3), 287298.CrossRefGoogle ScholarPubMed
Firth, J., Torous, J., Nicholas, J., Carney, R., Rosenbaum, S., & Sarris, J. (2017b). Can smartphone mental health interventions reduce symptoms of anxiety? A meta-analysis of randomized controlled trials. Journal of Affective Disorders, 218, 1522.CrossRefGoogle ScholarPubMed
Franzen, P. L., & Buysse, D. J. (2008). Sleep disturbances and depression: Risk relationships for subsequent depression and therapeutic implications. Dialogues in Clinical Neuroscience, 10(4), 473781.CrossRefGoogle ScholarPubMed
Glozier, N., Christensen, H., Griffiths, K. M., Hickie, I. B., Naismith, S. L., Biddle, D., … Ritterband, L. (2019). Adjunctive Internet-delivered cognitive behavioural therapy for insomnia in men with depression: A randomised controlled trial. Australian and New Zealand Journal of Psychiatry, 53(4), 350360.CrossRefGoogle ScholarPubMed
Goldstein, A. (1962). Therapist and patient expectancies in psychotherapy. New York: Macmillan.Google Scholar
Guo, S., Sun, W., Liu, C., & Wu, S. (2016). Structural validity of the Pittsburgh Sleep Quality Index in Chinese undergraduate students. Frontiers in Psychology, 7, 1126.CrossRefGoogle ScholarPubMed
Hagatun, S., Vedaa, Ø., Harvey, A. G., Nordgreen, T., Smith, O. R. F., Pallesen, S., … Sivertsen, B. (2018). Internet-delivered cognitive-behavioral therapy for insomnia and comorbid symptoms. Internet Interventions, 12, 1115.CrossRefGoogle ScholarPubMed
Hanson, K., Webb, T. L., Sheeran, P., & Turpin, G. (2016). Attitudes and preferences towards self-help treatments for depression in comparison to psychotherapy and antidepressant medication. Behavioural and Cognitive Psychotherapy, 44(2), 129139.CrossRefGoogle ScholarPubMed
Harris, L. M., Huang, X., Linthicum, K. P., Bryen, C. P., & Ribeiro, J. D. (2020). Sleep disturbances as risk factors for suicidal thoughts and behaviours: A meta-analysis of longitudinal studies. Scientific Reports, 10, 13888.CrossRefGoogle ScholarPubMed
Harvey, A. G., Murray, G., Chandler, R. A., & Soehner, A. (2011). Sleep disturbance as transdiagnostic: Consideration of neurobiological mechanisms. Clinical Psychology Review, 31(2), 225235.CrossRefGoogle ScholarPubMed
Ho, F. Y. Y., Chan, C. S., Lo, W. Y., & Leung, J. C. Y. (2020). The effect of self-help cognitive behavioral therapy for insomnia on depressive symptoms: An updated meta-analysis of randomized controlled trials. Journal of Affective Disorders, 265, 287304.CrossRefGoogle ScholarPubMed
Ho, F. Y. Y., Chung, K. F., Yeung, W. F., Ng, T. H. Y., & Cheng, S. K. W. (2014). Weekly brief phone support in self-help cognitive behavioral therapy for insomnia disorder: Relevance to adherence and efficacy. Behaviour Research and Therapy, 63, 147156.CrossRefGoogle ScholarPubMed
Ho, F. Y. Y., Yeung, W. F., Ng, T. H. Y., & Chan, C. S. (2016). The efficacy and cost-effectiveness of stepped care prevention and treatment for depressive and/or anxiety disorders: A systematic review and meta-analysis. Scientific Reports, 6, 29281.CrossRefGoogle ScholarPubMed
Horsch, C. H. G., Lancee, J., Griffioen-Both, F., Spruit, S., Fitrianie, S., Neerincx, M. A., … Brinkman, W. P. (2017). Mobile phone-delivered cognitive behavioral therapy for insomnia: A randomized waitlist controlled trial. Journal of Medical Internet Research, 19(4), e70.CrossRefGoogle ScholarPubMed
Hui, V. K. Y., Wong, C. Y. F., Ma, E. K. Y., Ho, F. Y. Y., & Chan, C. S. (2020). Treating depression with a smartphone-delivered self-help cognitive behavioral therapy for insomnia: Study protocol for a parallel group randomized controlled trial. Trials, 21, 843.CrossRefGoogle ScholarPubMed
Ibáñez, V., Silva, J., & Cauli, O. (2018). A survey on sleep assessment methods. Peer-reviewed Journal, 6, e4849.CrossRefGoogle ScholarPubMed
Kaufman, J., & Charney, D. (2000). Comorbidity of mood and anxiety disorders. Depression and Anxiety, 12, 6976.3.0.CO;2-K>CrossRefGoogle ScholarPubMed
Kazlauskas, E., Eimontas, J., Olff, M., Zelviene, P., & Andersson, G. (2020). Adherence predictors in internet-delivered self-help intervention for life stressors-related adjustment disorder. Frontiers in Psychiatry, 11, 137.CrossRefGoogle ScholarPubMed
Krieger, T., Urech, A., Duss, S. B., Blättler, L., Schmitt, W., Gast, H., … Berger, T. (2019). A randomized controlled trial comparing guided internet-based multi-component treatment and internet-based guided sleep restriction treatment to care as usual in insomnia. Sleep Medicine, 62, 4352.CrossRefGoogle Scholar
Lekander, M., Andreasson, A. N., Kecklund, G., Ekman, R., Ingre, M., Akerstedt, T., & Axelsson, J. (2013). Subjective health perception in healthy young men changes in response to experimentally restricted sleep and subsequent recovery sleep. Brain, Behavior, and Immunity, 34, 4346.CrossRefGoogle ScholarPubMed
Linardon, J., Cuijpers, P., Carlbring, P., Messer, M., & Fuller-Tyszkiewicz, M. (2019). The efficacy of app-supported smartphone interventions for mental health problems: A meta-analysis of randomized controlled trials. World Psychiatry, 18(3), 325336.CrossRefGoogle ScholarPubMed
Linardon, J., & Fuller-Tyszkiewicz, M. (2020). Attrition and adherence in smartphone-delivered interventions for mental health problems: A systematic and meta-analytic review. Journal of Consulting and Clinical Psychology, 88(1), 113.CrossRefGoogle ScholarPubMed
Liu, R. T., Steele, S. J., Hamilton, J. L., Do, Q. B. P., Furbish, K., Burke, T. A., … Gerlus, N. (2020). Sleep and suicide: A systematic review and meta-analysis of longitudinal studies. Clinical Psychology Review, 81, 101895. doi: 10.1016/j.cpr.2020.101895CrossRefGoogle ScholarPubMed
Mantani, A., Kato, T., Furukawa, T. A., Horikoshi, M., Imai, H., Hiroe, T., … Kawanishi, N. (2017). Smartphone cognitive behavioral therapy as an adjunct to pharmacotherapy for refractory depression: Randomized controlled trial. Journal of Medical Internet Research, 19(11), e373.CrossRefGoogle ScholarPubMed
Manzar, M. D., BaHammam, A. S., Hameed, U. A., Spence, D. W., Pandi-Perumal, S. R., Moscovitch, A., & Streiner, D. L. (2018). Dimensionality of the Pittsburgh Sleep Quality Index: A systematic review. Health and Quality of Life Outcomes, 16(1), 89.CrossRefGoogle ScholarPubMed
McClintock, S. M., Husain, M. M., Wisniewski, S. R., Nierenberg, A. A., Stewart, J. W., Trivedi, M. H., … Rush, A. J. (2011). Residual symptoms in depressed outpatients who respond by 50% but do not remit to antidepressant medication. Journal of Clinical Psychopharmacology, 31(2), 180186.CrossRefGoogle Scholar
Morin, C. M., Belleville, G., Bélanger, L., & Ivers, H. (2011). The Insomnia Severity Index: Psychometric indicators to detect insomnia cases and evaluate treatment response. Sleep, 34(5), 601608.CrossRefGoogle ScholarPubMed
Morin, C. M., & Espie, C. A. (2003). Insomnia: A clinical guide to assessment and treatment. New York: Kluwer Academic/Plenum.Google Scholar
Newman, M. G., Szkodny, L. E., Llera, S. J., & Przeworski, A. (2011). A review of technology-assisted self-help and minimal contact therapies for anxiety and depression: Is human contact necessary for therapeutic efficacy? Clinical Psychology Review, 31(1), 89103.CrossRefGoogle Scholar
Parker, G., Cheah, Y. C., & Roy, K. (2001). Do the Chinese somatize depression? A cross-cultural study. Social Psychiatry and Psychiatric Epidemiology, 36(6), 287293.CrossRefGoogle ScholarPubMed
Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1(3), 385401.CrossRefGoogle Scholar
Riemann, D. (2007). Insomnia and comorbid psychiatric disorders. Sleep Medicine, 8(Suppl 4), S15S20.CrossRefGoogle ScholarPubMed
Rost, T., Stein, J., Löbner, M., Kersting, A., Luck-Sikorski, C., & Riedel-Heller, S. G. (2017). User acceptance of computerized cognitive behavioral therapy for depression: Systematic review. Journal of Medical Internet Research, 19(9), e309.CrossRefGoogle ScholarPubMed
Salari, N., Hosseinian-Far, A., Jalali, R., Vaisi-Raygani, A., Rasoulpoor, S., Mohammadi, M., … Khaledi-Paveh, B. (2020). Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: A systematic review and meta-analysis. Globalization and Health, 16(1), 57.CrossRefGoogle ScholarPubMed
Santoft, F., Axelsson, E., Öst, L.-G., Hedman-Lagerlöf, M., Fust, J., & Hedman-Lagerlöf, E. (2019). Cognitive behaviour therapy for depression in primary care: Systematic review and meta-analysis. Psychological Medicine, 49(8), 12661274.CrossRefGoogle ScholarPubMed
Segal, S. P., Hodges, J. Q., & Hardiman, E. R. (2002). Factors in decisions to seek help from self-help and co-located community mental health agencies. American Journal of Orthopsychiatry, 72(2), 241249.CrossRefGoogle ScholarPubMed
Shi, W., Shen, Z. Z., Wang, S. Y., & Hall, B. J. (2020). Barriers to professional mental health help-seeking among Chinese adults: A systematic review. Frontiers in Psychiatry, 11, 442. doi: 10.3389/fpsyt.2020.00442CrossRefGoogle ScholarPubMed
Siebmanns, S., Johansson, P., Ulander, M., Johansson, L., Andersson, G., & Broström, A. (2021). The effect of nurse-led Internet-based cognitive behavioural therapy for insomnia on patients with cardiovascular disease: A randomized controlled trial with 6-month follow-up. Nursing Open, 8(4), 17551768.CrossRefGoogle ScholarPubMed
Sivertsen, B., Pallesen, S., Friborg, O., Nilsen, K. B., Bakke, Ø. K., Goll, J. B., & Hopstock, L. A. (2021). Sleep patterns and insomnia in a large population-based study of middle-aged and older adults: The Tromsø study 2015–2016. Journal of Sleep Research, 30(1), e13095.CrossRefGoogle Scholar
Snaith, R. P., & Zigmond, A. S. (1994). HADS: Hospital anxiety and depression scale. Windsor, Berkshire, UK: NFER-Nelson.Google Scholar
Tan, S. L., Storm, V., Reinwand, D. A., Wienert, J., de Vries, H., & Lippke, S. (2018). Understanding the positive associations of sleep, physical activity, fruit and vegetable intake as predictors of quality of life and subjective health across age groups: A theory based, cross-sectional web-based study. Frontiers in Psychology, 9, 977.CrossRefGoogle ScholarPubMed
Thorndike, F. P., Ritterband, L. M., Gonder-Frederick, L. A., Lord, H. R., Ingersoll, K. S., & Morin, C. M. (2013). A randomized controlled trial of an internet intervention for adults with insomnia: Effects on comorbid psychological and fatigue symptoms. Journal of Clinical Psychology, 69(10), 10781093.CrossRefGoogle ScholarPubMed
Torous, J., Lipschitz, J., Ng, M., & Firth, J. (2020). Dropout rates in clinical trials of smartphone apps for depressive symptoms: A systematic review and meta-analysis. Journal of Affective Disorders, 263, 413419.CrossRefGoogle ScholarPubMed
Tsai, P. S., Wang, S. Y., Wang, M. Y., Su, C. T., Yang, T. T., Huang, C. J., & Fang, S. C. (2005). Psychometric evaluation of the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI) in primary insomnia and control subjects. Quality of Life Research, 14(8), 19431952.CrossRefGoogle ScholarPubMed
Tsuno, N., Besset, A., & Ritchie, K. (2005). Sleep and depression. Journal of Clinical Psychiatry, 66(10), 12541269.CrossRefGoogle ScholarPubMed
van der Zweerde, T., van Straten, A., Effting, M., Kyle, S. D., & Lancee, J. (2019). Does online insomnia treatment reduce depressive symptoms? A randomized controlled trial in individuals with both insomnia and depressive symptoms. Psychological Medicine, 49(3), 501509.CrossRefGoogle ScholarPubMed
Vargas, I., & Perlis, M. L. (2020). Insomnia and depression: Clinical associations and possible mechanistic links. Current Opinion in Psychiatry, 34, 9599.CrossRefGoogle ScholarPubMed
Vedaa, Ø, Kallestad, H., Scott, J., Smith, O. R. F., Pallesen, S., Morken, G., … Sivertsen, B. (2020). Effects of digital cognitive behavioural therapy for insomnia on insomnia severity: A large-scale randomised controlled trial. The Lancet Digital Health, 2(8), e397e406.CrossRefGoogle ScholarPubMed
Vilagut, G., Forero, C. G., Barbaglia, G., & Alonso, J. (2016). Screening for depression in the general population with the center for epidemiologic studies depression (CES-D): A systematic review with meta-analysis. PLoS ONE, 11(5), e0155431.CrossRefGoogle Scholar
Ware, J. E., Kosinski, M., & Keller, S. D. (1995). SF-12: How to score the SF-12 physical and mental health summary scales. QualityMetric Incorporated.Google Scholar
Weinberg, M. K., Noble, J. M., & Hammond, T. G. (2016). Sleep well feel well: An investigation into the protective value of sleep quality on subjective well-being. Australian Journal of Psychology, 68, 9197.CrossRefGoogle Scholar
Wilhelm, S., Weingarden, H., Ladis, I., Braddick, V., Shin, J., & Jacobson, N. C. (2020). Cognitive-behavioral therapy in the digital age: Presidential address. Behavior Therapy, 51(1), 114.CrossRefGoogle ScholarPubMed
Wong, M. L., Lau, E. Y. Y., Wan, J. H. Y., Cheung, S. F., Hui, C. H., & Mok, D. S. Y. (2013). The interplay between sleep and mood in predicting academic functioning, physical health and psychological health: A longitudinal study. Journal of Psychosomatic Research, 74(4), 271277.CrossRefGoogle ScholarPubMed
Yang, J. M., Huang, Y. L., & Lin, S. W. (2008). Insomnia: A clinical guide to assessment and treatment. Taiwan: Psychological Publishing Co. (in Chinese)Google Scholar
Ye, Y. Y., Zhang, Y. F., Chen, J., Liu, J., Li, X. J., Liu, Y. Z., … Jiang, X. J. (2015). Internet-based cognitive behavioral therapy for insomnia (ICBT-i) improves comorbid anxiety and depression – A meta-analysis of randomized controlled trials. PLoS ONE, 10(11), e0142258.CrossRefGoogle ScholarPubMed
Zigmond, A. S., & Snaith, R. P. (1983). The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica, 67(6), 361370.CrossRefGoogle ScholarPubMed
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