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Major depression impairs incentive processing: evidence from the heart and the face

Published online by Cambridge University Press:  18 June 2018

Jessica Franzen ,
Kerstin Brinkmann ,
Guido H. E. Gendolla  and
Othman Sentissi
Jessica Franzen
Affiliation:
Geneva Motivation Laboratory, University of Geneva, Geneva, Switzerland
Kerstin Brinkmann*
Affiliation:
Geneva Motivation Laboratory, University of Geneva, Geneva, Switzerland
Guido H. E. Gendolla
Affiliation:
Geneva Motivation Laboratory, University of Geneva, Geneva, Switzerland
Othman Sentissi
Affiliation:
Department of Mental Health and Psychiatry, Geneva University Hospitals, Geneva, Switzerland
*
Author for correspondence: Kerstin Brinkmann, E-mail: Kerstin.Brinkmann@unige.ch
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Abstract

Background

The present study tested the hypothesis of a differential pattern of reward and punishment responsiveness in depression measuring effort mobilization during anticipation and facial expressions during consumption.

Methods

Twenty patients with major depressive disorder (MDD) and 20 control participants worked on a memory task under neutral, reward, and punishment instructions. Effort mobilization was operationalized as cardiovascular reactivity, while facial expressions were measured by facial electromyographic reactivity. Self-report measures for each phase complemented this multi-method approach.

Results

During anticipation, MDD patients showed weaker cardiac pre-ejection period (PEP) reactivity to reward and blunted self-reported wanting, but weaker PEP reactivity to punishment and unchanged self-reported avoidance motivation. During consumption, MDD patients showed reduced zygomaticus major muscle reactivity to reward and blunted self-reported liking, but unchanged corrugator supercilii muscle reactivity to punishment and unchanged self-reported disliking.

Conclusions

These findings demonstrate reduced effort mobilization during reward and punishment anticipation in depression. Moreover, they show reduced facial expressions during reward consumption and unchanged facial expressions during punishment consumption in depression.

Keywords

Depressioneffort mobilizationfacial expressionsincentive anticipationincentive consumptionpunishmentreward
Type
Original Articles
Information
Psychological Medicine , Volume 49 , Issue 6 , April 2019 , pp. 922 - 930
Copyright
Copyright © Cambridge University Press 2018 

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Footnotes

*

These authors shared first authorship.

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