Skip to main content Accessibility help
×
Home
Hostname: page-component-568f69f84b-r4dm2 Total loading time: 0.465 Render date: 2021-09-22T15:46:40.196Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Effects of a 4-week intervention with ready-made bioactive enriched pancakes on biomarkers of the metabolic syndrome

Published online by Cambridge University Press:  20 June 2016

S. Sutulic
Affiliation:
School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT
C. Bösch
Affiliation:
School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT
L. Marshall
Affiliation:
School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT
A. Bordoni
Affiliation:
Dipartimento di Scienze e Tecnologie Agro-Alimentari, Università di Bologna, Italy
H. Hingyi
Affiliation:
Adexgo Kft., Hungary
M. Muller
Affiliation:
AdWare Research Kft., Hungary
C. Orfila
Affiliation:
School of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT
Rights & Permissions[Opens in a new window]

Abstract

Type
Abstract
Copyright
Copyright © The Authors 2016 

In the UK it is estimated that 1 in 4 adults are at greater risk of heart disease and stroke due to presence of the metabolic syndrome (MetS)( 1 ). The MetS is a term used to describe any combination of at least three of the following conditions: high blood pressure, increased waist circumference, impaired fasting glucose, increased fasting triglycerides, and low HDL cholesterol.

Components of foods that may improve conditions associated with MetS include the omega-3 fatty acid docosahexaenoic acid (DHA) and the soluble plant fibre beta-glucan (BG), which are considered beneficial for maintaining normal blood triglyceride and cholesterol concentrations( 2 , 3 ). There is also clinical evidence that anthocyanins (AC) may improve HDL cholesterol in adults with dyslipidaemia(Reference Qin4).

In a double-blind, parallel-arm, randomised pilot study, 35 participants (M = 40 %), mean age 45 y, with or at risk of MetS were recruited to consume ready-made pancakes enriched with DHA, BG, or AC alone or in combinations of DHA + BG or DHA + AC every day for 4 weeks. At baseline and endpoint markers of MetS were measured. Mean change, from baseline to endpoint, in biomarkers of the MetS are summarised in Table 1.

Table 1: Mean change in biomarkers of the MetS. HDL-C, HDL cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation. Results were not statistically significant.

The objective of this pilot study was to select the enrichment type most effective at improving fasting blood triglycerides and/or HDL cholesterol, to be consumed in the subsequent PATHWAY-27 12-week placebo-controlled, multi-centre trial. Pancakes enriched with DHA and AC alone and in combination appear to be the most effective. DHA + AC enrichment was selected for further study.

References

1. Department of Health (2014) NHS Choices: Metabolic syndrome, http://www.nhs.uk/conditions/metabolic-syndrome/Pages/Introduction.aspx, (accessed January 2016).Google Scholar
2. EFSA Panel on Dietetic Products, Nutrition and Allergies (2010) EFSA Journal 8, (10), 1734.CrossRefGoogle Scholar
3. EFSA Panel on Dietetic Products, Nutrition and Allergies (2009) EFSA Journal 7, (9), 1254.CrossRefGoogle Scholar
4. Qin, et al. (2009) Am J Clin Nutr 90, 485492.CrossRefGoogle Scholar
Figure 0

Table 1: Mean change in biomarkers of the MetS. HDL-C, HDL cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation. Results were not statistically significant.

You have Access

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Effects of a 4-week intervention with ready-made bioactive enriched pancakes on biomarkers of the metabolic syndrome
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Effects of a 4-week intervention with ready-made bioactive enriched pancakes on biomarkers of the metabolic syndrome
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Effects of a 4-week intervention with ready-made bioactive enriched pancakes on biomarkers of the metabolic syndrome
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *