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Pregnancy-associated glycoprotein (PAG) in postpartum ewes

Published online by Cambridge University Press:  05 November 2021

M.J Ranilla ,
F.E. Gebbie ,
L.M. Mitchell ,
M. E. King ,
J.G. Skinner ,
J.F. Beckerst  and
J.J. Robinson
M.J Ranilla
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
F.E. Gebbie
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
L.M. Mitchell
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
M. E. King
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
J.G. Skinner
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
J.F. Beckerst*
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
J.J. Robinson
Affiliation:
Scottish Agricultural College, Ferguson Building, Craibstone Estate, Bucksburn, Aberdeen, AB 21 9YA. , United Kingdom
*
†Physiologie de la Reproduction, Faculté de Médecine Vétérinaire, Université de Liège, Belgium
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Extract

The mammalian placenta is an active endocrine organ capable of synthesising and secreting a wide range of hormones and proteins. Pregnancy-associated glycoprotein (PAG) is one of these. It is produced by the binucleate cells of the placenta and becomes detectable in the maternal circulation soon after implantation (Zoli et al., 1992a). PAG occurs in cattle (bPAG), goats and sheep (oPAG), and has been used for early pregnancy diagnosis and the detection of embryonic death (Ranilla et al., 1994).

In the postpartum cow bPAG has a slow disappearance rate and is detectable in maternal serum until 100 days after calving (Zoli et al., 1992b). The present work was carried out to determine the rate of decline of oPAG in postpartum ewes and to test if the disappearance rate differed with litter size, age and diet.

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Information
Proceedings of the British Society of Animal Science , Volume 1997 , 1997 , pp. 185
Copyright
Copyright © British Society of Animal Science 1997

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References

Ranilla, M.J., Sulon, J., Cairo, M.D., Mantecón, A.R. and Beckers, J.F (1994). Theriogenology, 42: 537–545.CrossRefGoogle Scholar
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Zoli, A.P., Demez, P., Beckers, J.F., Reznik, M. and Beckers, J.F. (1992a). Biology of Reproduction 46: 623–629.CrossRefGoogle Scholar
Zoli, A.P, Guilbaut, L.A., Delahaut, Ph., Benitez-Ortiz, W and Beckers, J.F. (1992b). Biology of Reproduction 46: 83–92.CrossRefGoogle Scholar