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The effect of respiratory disease on various acute phase protein levels in the slaughter pig

Published online by Cambridge University Press:  20 November 2017

J.R. Amory
Affiliation:
Animal Science Research Centre, Harper Adams University College, Newport, Shropshire, TF10 8NB, UK
A.M. Mackenzie
Affiliation:
Animal Science Research Centre, Harper Adams University College, Newport, Shropshire, TF10 8NB, UK
G.P. Pearce
Affiliation:
Animal Science Research Centre, Harper Adams University College, Newport, Shropshire, TF10 8NB, UK
P.D. Eckersall
Affiliation:
University of Glasgow Veterinary School, Bearsden Rd, Glasgow, G61 1QH, UK
F. Lampreave
Affiliation:
University of Zaragosa, 12 Pedro Cerbuno, 50009 Zaragoza, Spain
M.A. Alava
Affiliation:
University of Zaragosa, 12 Pedro Cerbuno, 50009 Zaragoza, Spain
M.A. Varley
Affiliation:
SCA Nutrition Limited Maple Mill Dalton Airfield Industrial Estate, Dalton, Thirsk, North Yorkshire, YO7 3HE, UK
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Extract

Respiratory health is an important aspect of pig production due to its effects on pig performance and welfare. Haptoglobin, an acute phase protein, has been identified as a sensitive indicator of infection with respiratory pathogens such as Actinobacillus pleuropneumoniae and has been suggested as a possible marker for non-specific surveillance of pig health status (Heergaard et al., 1998). Other acute phase proteins such as Major Acute Phase protein (MAP) and Serum Amyloid A (SAA) may also be of use in disease surveillance. However, little is known about the variation of these proteins and their associations with post-mortem signs of disease in the pig. This information could be of importance in monitoring herd health and in facilitating ante- and post-mortem inspection by identifying diseased animals. This study was designed to determine whether various acute phase proteins could be used to identify enzootic or pleuropneumonia in individual pigs or farms with increased prevalence of these diseases.

Type
Threatre Presentations
Copyright
Copyright © The British Society of Animal Science 2001

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References

Heergaard, P.M., Klausen, J., Nielsen, J.P., Gonzalez-Ramon, N., Pineiro, M., Lampreave, F. and Alava, M.A. 1998. The porcine acute phase response to infection with Actinobacillus pleuropneumoniae. Haptoglobin, C-reactive protein, major acute phase protein and serum amyloid A protein are sensitive indicators of infection. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 119: 365373.CrossRefGoogle Scholar
Horadagoda, N.U., Knox, K.M.G., Gibbs, H.A., Reid, S.W.J, Horadagoda, A., Edwards, S.E.R. and Eckersall, P.D. 1999. Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Veterinary Record 144: 437441.CrossRefGoogle Scholar

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