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Profiling of triterpenoid saponin content variation in different chemotypic accessions of Centella asiatica L.

Published online by Cambridge University Press:  03 September 2014

Jyoti Singh ,
Rajender Singh Sangwan ,
Sanjeev Gupta ,
Sangeeta Saxena  and
Neelam S. Sangwan
Jyoti Singh
Affiliation:
Metabolic and Structural Biology Department, CSIR–Central Institute for Medicinal and Aromatic Plants (CSIR–CIMAP), Lucknow226 015, UP, India
Rajender Singh Sangwan
Affiliation:
Metabolic and Structural Biology Department, CSIR–Central Institute for Medicinal and Aromatic Plants (CSIR–CIMAP), Lucknow226 015, UP, India
Sanjeev Gupta
Affiliation:
Metabolic and Structural Biology Department, CSIR–Central Institute for Medicinal and Aromatic Plants (CSIR–CIMAP), Lucknow226 015, UP, India
Sangeeta Saxena
Affiliation:
Department of Biotechnology, Babasaheb Bhimrao Ambedkar University, Rai Bareilly Road, Lucknow226 025, UP, India
Neelam S. Sangwan*
Affiliation:
Metabolic and Structural Biology Department, CSIR–Central Institute for Medicinal and Aromatic Plants (CSIR–CIMAP), Lucknow226 015, UP, India
*
*Corresponding author. E-mail: nss.cimap@gmail.com
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Abstract

Centella asiatica (L.) Urban is an important herbaceous medicinal plant with a worldwide distribution. The herb possesses a medicinal value and is used extensively in traditional systems of medicine. The medicinal properties of the herb are attributed to the presence of characteristic triterpenoids and their saponins in the leaves. The major triterpenoids are asiaticoside, madecassoside and their aglycones asiatic acid and madecassic acid, respectively, among others. The present study reports a remarkable qualitative and quantitative variability in secondary metabolites in different accessions of C. asiatica L. as determined by high-performance liquid chromatography (HPLC) analysis. The accessions analyzed in this study can be considered as the core set of discrete chemotypes of C. asiatica. Considerable and contrasting biochemical variations were observed in the terpenoid profiles of the chemotypes. From the basic and applied phytochemical utility, this chemotypic variability in the total content of triterpenoids is important and interesting.

Keywords

asiaticosides; Centella asiaticachemotypestriterpenoids
Type
Short Communication
Information
Plant Genetic Resources , Volume 13 , Issue 2 , August 2015 , pp. 176 - 179
Copyright
Copyright © NIAB 2014 

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