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Synthesis of water-soluble, magnetic Fe/Au nanoparticles

Published online by Cambridge University Press:  01 February 2011

Katherine A. Brown
Affiliation:
kabrown@mit.edu, Massachusetts Institute of Technology, Biological Engineering, 77 Massachusetts ave, 56-354, Cambridge, Ma, 02139, United States, 617-324-0250
Andy Wijaya
Affiliation:
wijaya@mit.edu, Massachusetts Institute of Technology, Chemical Engineering, United States
Joshua D Alper
Affiliation:
jalper@mit.edu, Massachusetts Institute of Technology, Mechanical Engineering, United States
Kimberly Hamad-Schifferli
Affiliation:
schiffer@mit.edu, Massachusetts Institute of Technology, Mechanical Engineering and Biological Engineering, United States
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Abstract

We report the synthesis of water soluble, monodisperse Fe/Au bimetallic nanoparticles with an average diameter of 7nm. Synthesis involves simultaneous reduction of Fe3+ and Au3+ in water to yield bimetallic nanoparticles. The elemental content of Fe is 1.5%. Nanoparticles exhibit ferromagnetic behavior as measured by SQUID. These particles can be easily conjugated to thiolated DNA, as evidenced by mobility shifts in agarose gel electrophoresis. Nanoparticles heat in solution to temperatures above 40°C, indicating suitability for hyperthermia.

Type
Research Article
Copyright
Copyright © Materials Research Society 2006

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