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Study of Biosensors Based on Fe Nanowires

Published online by Cambridge University Press:  31 January 2011

Yang hao  and
Chen Yuquan
Yang hao
Affiliation:
yanghaoyanghao@sina.com, Zhejiang University, Biomedical Engineering, Hangzhou, Zhejiang, China
Chen Yuquan
Affiliation:
yqchen@mail.bme.zju.edu.cn, Zhejiang University, Biomedical Engineering, Hangzhou, Zhejiang, China
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Abstract

Anodic aluminum oxide (AAO) template was prepared by using anodizing voltage step-decreasing method after two-step oxide method. Based on AAO template, Fe nanowires arrays were electrochemically deposited. Fe nanowires were coated by chitosan. Fe nanowires/chitosan was synthesized by glutaraldehyde as cross-linking reagent. By crosslinking α-human chorionic gonadotropin (α-HCG), biological probes with Fe nanowires/chitosan/antibody were prepared. An easy operating, easy taking and rapid reacting magnetic detecting system was developed after optimizing the geometry parameters of detect coil. Different concentration samples with 1, 2 and 5 g(Fe)/L were detected. The results show that the sensitivity of system is 0.2 g(Fe)/L and can be improve better.

Keywords

nanostructurebiomedicalelectrodeposition
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1191: Symposium OO – Materials and Strategies for Lab-on-a-Chip–Biological Analysis, Cell-Material Interfaces and Fluidic Assembly of Nanostructures , 2009 , 1191-OO10-04
Copyright
Copyright © Materials Research Society 2009

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