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The Resorbable Bioglassceramics Based on Calcium Biophosphate

Published online by Cambridge University Press:  15 February 2011

Tsung-Shune Chin ,
D. C. Wu ,
H. S. Liu ,
M. P. Hung  and
C. P. Wang
Tsung-Shune Chin
Affiliation:
Department of Materials Science and Engineering, Tsing Hua University, Hsinchu, 300, Taiwan, Republic of China
D. C. Wu
Affiliation:
Department of Materials Engineering, Chen Kung University, Tainan, 701, Taiwan, Republic of China
H. S. Liu
Affiliation:
Department of Materials Science and Engineering, Tsing Hua University, Hsinchu, 300, Taiwan, Republic of China
M. P. Hung
Affiliation:
Department of Materials Engineering, Chen Kung University, Tainan, 701, Taiwan, Republic of China
C. P. Wang
Affiliation:
Department of Biology, Cheng Kung University, Tainan, 701, Taiwan, Republic of China
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Abstract

Novel resorbable bioglassceramic artificial tooth roots based on calcium biphosphate were synthesized, implanted into rabbits, and assessed. They were prepared by melting a glass composition of CaO/(CaO+P205) = 0.33, casting, crushing, loose powder sintering and crystallization annealing. The resultant porosity is 3 to 36 μm. The three point bending strength is 33 to 150 MPa depending on annealing treatment. The crystallized phases are β-Ca2P2O7 and CaP206. These porous implants show remarkable biocompatibility with the old bone and induce the growth of new bone within 30 days. The implants are partly resorbed after 90 days and replaced by new bone. The ingrowth of blood vessels into the implant is abundantly seen after 90 days despite a small original porosity, due probably to enlarged pores by preferential resorption of the implant material. The new ceramics are good candidates for resorbable bone bioimplant.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 252: Symposium T – Tissue-Inducing Biomaterials , 1991 , 103
Copyright
Copyright © Materials Research Society 1992

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References

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