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Poly(1,3-Butylene Fumerate) and Poly(1,3-Butylene Fumerate)-co-(1,3-Butylene Maleate) as Electrospun Scaffold Materials

Published online by Cambridge University Press:  31 January 2011

Kirsten Nicole Cicotte ,
Shawn M. Dirk  and
Elizabeth Hedberg-Dirk
Kirsten Nicole Cicotte
Affiliation:
kcicott@sandia.gov, University of New Mexico, Center for Biomedical Engineering, 1 University New Mexico, MSC 01 1141, Albuquerque, New Mexico, 87131, United States
Shawn M. Dirk
Affiliation:
smdirk@sandia.gov, Sandia National Laboratories, Organic Materials, P.O. Box 5800, MS 0888, Albuquerque, New Mexico, 87185, United States
Elizabeth Hedberg-Dirk
Affiliation:
edirk@unm.edu, University of New Mexico, Chemical and Nuclear Engineering, Center for Biomedical Engineering, MSC01 1141, 2041 Centennial Engineering Center, Albuquerque, New Mexico, 87131-0001, United States, 505-277-5906
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Abstract

Poly(butylene fumerate) (PBF) and poly(butylene fumerate)-co-(butylene maleate) (PBFcBM) have been synthesized from the ring opening and condensation reactions of maleic anhydride (MA) and 1,3-butanediol (BD). PBFcBM synthesized in this way contains greater than 85% maleate groups. Both PBF and PBFcBM have a glass transition temperature (Tg) below room temperature and therefore cannot be electrospun using the conventional electrospinning process as a non-porous film results. To facilitate production of nonwoven micro- and nano-fiber mats, a UV-source (λ=356 nm) was used in combination with a photoinitator loaded polymer solution to initiate the crosslinking reaction of the fumerate and maleate functional groups as the fibers were produced. The resulting non-woven fiber mats are potentially suitable scaffolds for tissue engineering and drug delivery application.

Keywords

biomaterialpolymerbiomedical
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1239: Symposium VV – Micro- and Nanoscale Processing of Biomaterials , 2009 , 1239-VV05-02
Copyright
Copyright © Materials Research Society 2010

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