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A Novel and Low-Cost Disposable Device for Phototherapy of Neonatal Jaundice

Published online by Cambridge University Press:  31 January 2011

Giovana R Ferreira
Affiliation:
giovanaribeiro_ufop@yahoo.com.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Cláudia K. B. de Vasconcelos
Affiliation:
ckbvasconcelos@iceb.ufop.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Mariana M Silva
Affiliation:
mms1985@uol.com.br, Universidade Federal de Ouro Preto, Departamento de Fisica, Ouro Preto, Minas Geraes, Brazil
Fabrício A dos Santos
Affiliation:
santosfrabricio@gmail.com, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Jorge G. Pires
Affiliation:
jorgeguerrapires@gmail.com, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
André S Duarte
Affiliation:
asdzin@gmail.com, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Andrea Gomes Campos Bianchi
Affiliation:
andrea@iceb.ufop.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Rodrigo Fernando Bianchi
Affiliation:
bianchi@iceb.ufop.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
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Abstract

The present work details, to our knowledge, the first examination of the influence of blue-light radiation on the optical properties of organic luminescent films in attempting to develop an indicator dosimeter for phototherapy of neonatal jaundice. Jaundice is the most common problem encountered in newborns due to immature functioning in the liver. The operating principle of the device is based on the optical response of poly[2-methoxy-5-(2'-ethylhexyloxy)-p-phenylene (MEH-PPV) and tris(8-hydroxyquinolinato) aluminum (Alq3) materials dispersed in polystyrene (PS) matrix (denoted as PS/MEH-PPV/Alq3). It is observed a blue-shift on the photoluminescence of PS/MEH-PPV/Alq3 system from red to orange-yellow, and then to green as function of the blue-light radiation exposure time. The result is attributed to the spectral overlap between emission of Alq3 and absorption of MEH-PPV. The optical response of PS/MEH-PPV/Alq3 to radiation was investigated to design a low-cost (< US$ 0.05) “smart” sensor to represent easily the radiation dosage normally used in blue-light phototherapy. The basic idea behind this concept considers the sensor as a traffic light device, where red represents underdose and green the prescription dose or overdose, while orange-yellow suggests that radiation therapy is an ongoing process. This personal real-time radiation dosimeter appears here as a key requirement for successful development of innovations in effective management of the radiation dose planning before treatment of neonatal where control of dose absorption of infants is extremely important.

Type
Research Article
Copyright
Copyright © Materials Research Society 2010

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References

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