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Covalently-linked Adducts of Single-walled Nanotubes with Biomolecules: Synthesis, Hybridization, and Biologically-Directed Surface Assembly

Published online by Cambridge University Press:  11 February 2011

Sarah E. Baker
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
Tami L. Lasseter
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
Lloyd M. Smith
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
Robert J. Hamers
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
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Abstract

Covalently-linked adducts of single-walled carbon nanotubes (SWNTs) with biomolecules have been fabricated. Results are presented here for DNA-SWNT and for biotin-SWNT adducts. DNA-SWNT adducts are shown to be biochemically accessible and to exhibit high selectivity, favoring hybridization with complementary vs. non-complementary DNA sequences. Biotin-SWNT adducts were also prepared and used to direct the assembly of nanotubes onto a biotinylated glass surface.

Type
Research Article
Copyright
Copyright © Materials Research Society 2003

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References

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Covalently-linked Adducts of Single-walled Nanotubes with Biomolecules: Synthesis, Hybridization, and Biologically-Directed Surface Assembly
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Covalently-linked Adducts of Single-walled Nanotubes with Biomolecules: Synthesis, Hybridization, and Biologically-Directed Surface Assembly
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