Hostname: page-component-8448b6f56d-42gr6 Total loading time: 0 Render date: 2024-04-24T11:48:10.124Z Has data issue: false hasContentIssue false
  • English
  • Français

Biocompatible luminescent nanoparticles on the basis of calcium phosphate

Published online by Cambridge University Press:  29 July 2011

Sofia Dembski ,
Moritz Milde ,
Emeline Dassonneville ,
Carsten Gellermann ,
Torsten Klockenbring ,
Marcel Dyrba  and
Stefan Schweizer
Sofia Dembski
Affiliation:
Fraunhofer Institute for Silicate Research ISC, Neunerplatz 2, Wuerzburg, 97082, Germany
Moritz Milde
Affiliation:
Fraunhofer Institute for Silicate Research ISC, Neunerplatz 2, Wuerzburg, 97082, Germany
Emeline Dassonneville
Affiliation:
Fraunhofer Institute for Silicate Research ISC, Neunerplatz 2, Wuerzburg, 97082, Germany
Carsten Gellermann
Affiliation:
Fraunhofer Institute for Silicate Research ISC, Neunerplatz 2, Wuerzburg, 97082, Germany
Torsten Klockenbring
Affiliation:
Fraunhofer Institute for Molecular Biology and Applied Ecology, Forckenbeckstr. 6, Aachen, 52074, Germany
Marcel Dyrba
Affiliation:
Centre for Innovation Competence SiLi-nano®, Martin Luther University of Halle-Wittenberg, Karl-Freiherr-von-Fritsch-Str. 3, Halle (Saale), 06120, Germany
Stefan Schweizer
Affiliation:
Centre for Innovation Competence SiLi-nano®, Martin Luther University of Halle-Wittenberg, Karl-Freiherr-von-Fritsch-Str. 3, Halle (Saale), 06120, Germany Fraunhofer Center for Silicon Photovoltaics, Walter-Hülse-Str. 1, Halle (Saale), 06120, Germany
Get access

Abstract

Luminescent lanthanide doped SiO2/Hydroxylapatite (HAp) core/shell nanoparticles (NPs) were synthesized by sol-gel technology. The resulting NPs exhibited an amorphous SiO2 core and a crystalline luminescent shell. The formation of the HAp layer was possible at pH 8.5. The characterization of the resulting NPs was done by transmission electron microscopy, X-ray diffraction analysis, inductively-coupled plasma combined with optical emission spectrometry, and photoluminescence spectroscopy. Additionally, the newly developed SiO2/HAp:Ln3+ core/shell NPs were tested for their biocompatibility, e. g. by an in vitro cell culture based assay.

Keywords

core/shellluminescencecolloid
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1355: Symposium JJ – Biological Hybrid Materials for Life Sciences , 2011 , mrss11-1355-jj05-04
Copyright
Copyright © Materials Research Society 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Dorozhkin, S.V. and Epple, M., Angew. Chem. Int. Ed. 41, 3130 (2002).10.1002/1521-3773(20020902)41:17<3130::AID-ANIE3130>3.0.CO;2-13.0.CO;2-1>Google Scholar
2. Mondéjar, S.P., Kovtun, A. and Epple, M., J. Mater. Chem. 17, 4153 (2007).10.1039/b708258dGoogle Scholar
3. Doat, A., Pelle, F., Gardant, N. and Lebugle, A., J. Solid State Chem. 177, 1179 (2004).10.1016/j.jssc.2003.10.023Google Scholar
4. Uskoković, V. and Uskoković, D.P., J. Biomed. Mater. Res. Part B 96B, 152 (2011).10.1002/jbm.b.31746Google Scholar
5. Mondéjar, S.P., Kovtun, A. and Epple, M., J. Mater. Chem. 17, 4153 (2007).10.1039/b708258dGoogle Scholar
6. Dembski, S., Milde, M., Klockenbring, T., Dyrba, M., Schweizer, S. and Gellermann, C., Langmuir, submitted (2011). .Google Scholar
7. Stoeber, W., Fink, A. and Bohn, E., J. Colloid Interface Sci. 26, 62 (1968).10.1016/0021-9797(68)90272-5Google Scholar
8. Dembski, S., Rupp, S., Milde, M., Gellermann, C., Dyrba, M., Schweizer, S., Batentschuk, M., Osvet, A. and Winnacker, A., Opt. Mater. 33, 1106 (2011).10.1016/j.optmat.2010.10.036Google Scholar
9. Yu, M., Wang, H., Lin, C. K., Li, G. Z. and Lin, J., Nanotechnology 17, 3245 (2006).10.1088/0957-4484/17/13/028Google Scholar
10. Stern, S.T., Zolnik, B. S., McLeland, C.B., Clogston, J., Zheng, J. and McNei, S.E., Toxicol. Sci. 106, 140 (2008).10.1093/toxsci/kfn137Google Scholar
11. Binnemans, K., Van Deun, R., Görller-Walrand, C. and Adam, J.L., J. Non-Cryst. Solids 238, 11 (1998).10.1016/S0022-3093(98)00540-7Google Scholar
12. Seltzer, M.D., Wright, A., Morrison, C.A., Wortman, D.E., Gruber, J.B. and Filert, E.D., J. Phys. Chem. Solids. 57, 1175 (1996).10.1016/0022-3697(95)00248-0Google Scholar
13. Elliott, J.C., Wilson, R.M. and Dowker, S.E.P., Adv. X-Ray Anal. 45, 172 (2001).Google Scholar
14. Fowler, B.O., Inorg. Chem. 13, 194 (1974).10.1021/ic50131a039Google Scholar