The presence of copolymers at an interface between two immiscible fluids is crucial to such processes as emulsion stabilization and microemulsion formation [1]. Recently Marques and Joanny [2] and Garel et al. [3] have studied the behavior of a random copolymer at a liquid-liquid interface. However, the arrangement or sequence distribution of the monomers in a copolymer can vary widely from random to blocky or purely alternating. In this paper, we use both analytic arguments and molecular dynamics simulations to determine how the sequence distribution affects the adsorption and conformation of a single macromolecule at the boundary between two immiscible fluids [4]. In particular, we derive an expression for the free energy of a copolymer at the interface and compare the resulting predictions with the outcome of the simulations. Our findings yield design criteria for fabricating polymers that display the desired interfacial properties.