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The contribution of cell-cell signaling and motility to bacterial biofilm formation

Published online by Cambridge University Press:  18 May 2011

Joshua D. Shrout ,
Tim Tolker-Nielsen ,
Michael Givskov  and
Matthew R. Parsek
Joshua D. Shrout
Affiliation:
University of Notre Dame, IN 46556, USA; joshua.shrout@nd.edu
Tim Tolker-Nielsen
Affiliation:
University of Copenhagen, Denmark; ttn@sund.ku.dk
Michael Givskov
Affiliation:
University of Copenhagen, Denmark; mgivskov@sund.ku.dk
Matthew R. Parsek
Affiliation:
University of Washington, Seattle 98195, USA; parsem@u.washington.edu
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Abstract

Many bacteria grow attached to a surface as biofilms. Several factors dictate biofilm formation, including responses by the colonizing bacteria to their environment. Here we review how bacteria use cell-cell signaling (also called quorum sensing) and motility during biofilm formation. Specifically, we describe quorum sensing and surface motility exhibited by the bacterium Pseudomonas aeruginosa, a ubiquitous environmental organism that acts as an opportunistic human pathogen in immunocompromised individuals. P. aeruginosa uses acyl-homoserine lactone signals during quorum sensing to synchronize gene expression important to the production of polysaccharides, rhamnolipid, and other virulence factors. Surface motility affects the assembly and architecture of biofilms, and some aspects of motility are also influenced by quorum sensing. While some genes and their function are specific to P. aeruginosa, many aspects of biofilm development can be used as a model system to understand how bacteria differentially colonize surfaces.

Type
Research Article
Information
MRS Bulletin , Volume 36 , Issue 5: All together now: Integrating biofilm research across disciplines , May 2011 , pp. 367 - 373
Copyright
Copyright © Materials Research Society 2011

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References

1.Geesey, G.G., Mutch, R., Costerton, J.W., Green, R.B., Limn. Ocean. 23, 6 (1978).CrossRefGoogle Scholar
2.Molin, S., Tolker-Nielsen, T., Curr. Opin. Biotechnol. 14, 3 (2003).CrossRefGoogle Scholar
3.Emtiazi, F., Schwartz, T., Marten, S.M., Krolla-Sidenstein, P., Obst, U., Water Res. 38, 5 (2004).CrossRefGoogle Scholar
4.Stover, C.K., Pham, X.Q., Erwin, A.L., Mizoguchi, S.D., Warrener, P., Hickey, M.J., Brinkman, F.S., Hufnagle, W.O., Kowalik, D.J., Lagrou, M., Garber, R.L., Goltry, L., Tolentino, E., Westbrock-Wadman, S., Yuan, Y., Brody, L.L., Coulter, S.N., Folger, K.R., Kas, A., Larbig, K., Lim, R., Smith, K., Spencer, D., Wong, G.K., Wu, Z., Paulsen, I.T., Reizer, J., Saier, M.H., Hancock, R.E., Lory, S., Olson, M.V., Nature 406, 6799 (2000).CrossRefGoogle Scholar
5.Lyczak, J.B., Cannon, C.L., Pier, G.B., Microbes Infect. 2, 9 (2000).CrossRefGoogle Scholar
6.Banin, E., Vasil, M.L., Greenberg, E.P., Proc. Natl. Acad. Sci. U.S.A. 102, 31 (2005).Google Scholar
7.Fuqua, C., Parsek, M.R., Greenberg, E.P., Annu. Rev. Genet. 35 (2001).CrossRefGoogle Scholar
8.Fuqua, C., Greenberg, E.P., Nat. Rev. Mol. Cell Biol. 3, 9 (2002).CrossRefGoogle Scholar
9.Miller, M.B., Bassler, B.L., Annu. Rev. Microbiol. 55 (2001).CrossRefGoogle Scholar
10.Taga, M.E., Bassler, B.L., Proc. Natl. Acad. Sci. U.S.A. 100 (2003).Google Scholar
11.Fuqua, C., Greenberg, E.P., Curr. Opin. Microbiol. 1, 2 (1998).CrossRefGoogle Scholar
12.Whitehead, N.A., Barnard, A.M.L., Slater, H., Simpson, N.J.L., Salmond, G.P.C., FEMS Microbiol. Rev. 25, 4 (2001).Google Scholar
13.de Kievit, T.R., Kakai, Y., Register, J.K., Pesci, E.C., Iglewski, B.H., FEMS Microbiol. Lett. 212, 1 (2002).Google Scholar
14.Whiteley, M., Lee, K.M., Greenberg, E.P., Proc. Natl. Acad. Sci. U.S.A. 96, 24 (1999).CrossRefGoogle Scholar
15.Wagner, V.E., Bushnell, D., Passador, L., Brooks, A.I., Iglewski, B.H., J. Bacteriol. 185, 7 (2003).CrossRefGoogle Scholar
16.Arevalo-Ferro, C., Hentzer, M., Reil, G., Gorg, A., Kjelleberg, S., Givskov, M., Riedel, K., Eberl, L., Environ. Microbiol. 5, 12 (2003).CrossRefGoogle Scholar
17.Schuster, M., Lostroh, C.P., Ogi, T., Greenberg, E.P., J. Bacteriol. 185, 7 (2003).Google Scholar
18.McGrath, S., Wade, D.S., Pesci, E.C., FEMS Microbiol. Lett. 230, 1 (2004).CrossRefGoogle Scholar
19.Bjarnsholt, T., Jensen, P.O., Fiandaca, M.J., Pedersen, J., Hansen, C.R., Andersen, C.B., Pressler, T., Givskov, M., Hoiby, N., Pediatr. Pulmonol. 44, 6 (2009).CrossRefGoogle Scholar
20.Kirketerp-Moller, K., Jensen, P.O., Fazli, M., Madsen, K.G., Pedersen, J., Moser, C., Tolker-Nielsen, T., Hoiby, N., Givskov, M., Bjarnsholt, T., J. Clin. Microbiol. 46, 8 (2008).CrossRefGoogle Scholar
21.Davies, D.G., Parsek, M.R., Pearson, J.P., Iglewski, B.H., Costerton, J.W., Greenberg, E.P., Science 280, 5361 (1998).Google Scholar
22.Heydorn, A., Ersboll, B., Kato, J., Hentzer, M., Parsek, M.R., Tolker-Nielsen, T., Givskov, M., Molin, S., Appl. Environ. Microbiol. 68, 4 (2002).Google Scholar
23.de Kievit, T.R., Gillis, R., Marx, S., Brown, C., Iglewski, B.H., Appl. Environ. Microbiol. 67, 4 (2001).Google Scholar
24.Kirisits, M.J., Margolis, J.J., Purevdorj-Gage, B.L., Vaughan, B., Chopp, D.L., Stoodley, P., Parsek, M.R., J. Bacteriol. 189, 22 (2007).CrossRefGoogle Scholar
25.Purevdorj, B., Costerton, J.W., Stoodley, P., Appl. Environ. Microbiol. 68, 9 (2002).CrossRefGoogle Scholar
26.Stoodley, P., Jacobsen, A., Dunsmore, B.C., Purevdorj, B., Wilson, S., Lappin-Scott, H.M., Costerton, J.W., Water Sci. Technol. 43, 6 (2001).CrossRefGoogle Scholar
27.Folsom, J., Richards, L., Pitts, B., Roe, F., Ehrlich, G., Parker, A., Mazurie, A., Stewart, P., BMC Microbiol. 10, 1 (2010).CrossRefGoogle Scholar
28.Whiteley, M., Bangera, M.G., Bumgarner, R.E., Parsek, M.R., Teitzel, G.M., Lory, S., Greenberg, E.P., Nature 413, 6858 (2001).Google Scholar
29.Shrout, J.D., Chopp, D.L., Just, C.L., Hentzer, M., Givskov, M., Parsek, M.R., Mol. Microbiol. 62, 5 (2006).Google Scholar
30.Bollinger, N., Hasset, D.J., Iglewski, B.H., Costerton, J.W., McDermott, T.R., J. Bacteriol. 183, 6 (2001).CrossRefGoogle Scholar
31.Davey, M.E., Caiazza, N.C., O’Toole, G.A., J. Bacteriol. 185, 3 (2003).Google Scholar
32.Pamp, S.J., Tolker-Nielsen, T., J. Bacteriol. 189, 6 (2007).CrossRefGoogle Scholar
33.Alhede, M., Bjarnsholt, T., Jensen, P.O., Phipps, R.K., Moser, C., Christophersen, L., Christensen, L.D., van Gennip, M., Parsek, M., Hoiby, N., Rasmussen, T.B., Givskov, M., Microbiology 155, Pt 11 (2009).Google Scholar
34.Jensen, P.O., Bjarnsholt, T., Phipps, R., Rasmussen, T.B., Calum, H., Christoffersen, L., Moser, C., Williams, P., Pressler, T., Givskov, M., Hoiby, N., Microbiology 153, Pt 5 (2007).CrossRefGoogle Scholar
35.Winzer, K., Falconer, C., Garber, N.C., Diggle, S.P., Camara, M., Williams, P., J. Bacteriol. 182, 22 (2000).Google Scholar
36.Banin, E., Vasil, M.L., Greenberg, E.P., Proc. Natl. Acad. Sci. U.S.A. 102, 31 (2005).Google Scholar
37.Mattick, J.S., Annu. Rev. Microbiol. 56, 1 (2002).Google Scholar
38.Murray, T.S., Kazmierczak, B.I., J. Bacteriol. 190, 8 (2008).CrossRefGoogle Scholar
39.Caiazza, N.C., Shanks, R.M., O’Toole, G.A., J. Bacteriol. 187, 21 (2005).CrossRefGoogle Scholar
40.Déziel, E., Lépine, F., Milot, S., Villemur, R., Microbiology 149, 8 (2003).CrossRefGoogle Scholar
41.Köhler, T., Curty, L.K., Barja, F., van Delden, C., Pechére, J.C., J. Bacteriol. 182, 21 (2000).CrossRefGoogle Scholar
42.Ochsner, U.A., Fiechter, A., Reiser, J., Journal of Biological Chemistry 269, 31 (1994).Google Scholar
43.Overhage, J., Lewenza, S., Marr, A.K., Hancock, R.E., J. Bacteriol. 189, 5 (2007).CrossRefGoogle Scholar
44.Nadal Jimenez, P., Koch, G., Papaioannou, E., Wahjudi, M., Krzeslak, J., Coenye, T., Cool, R.H., Quax, W.J., Microbiology 156, Pt 1 (2010).Google Scholar
45.Yeung, A.T.Y., Torfs, E.C.W., Jamshidi, F., Bains, M., Wiegand, I., Hancock, R.E.W., Overhage, J., J. Bacteriol. 191 (18), 5592 (2009).CrossRefGoogle Scholar
46.Glick, R., Gilmour, C., Tremblay, J., Satanower, S., Avidan, O., Deziel, E., Greenberg, E.P., Poole, K., Banin, E., J. Bacteriol. 12 (192), 2973 (2010).Google Scholar
47.Barken, K.B., Pamp, S.J., Yang, L., Gjermansen, M., Bertrand, J.J., Klausen, M., Givskov, M., Whitchurch, C.B., Engel, J.N., Tolker-Nielsen, T., Environ. Microbiol. 10, 9 (2008).Google Scholar
48.Klausen, M., Aaes-Jørgensen, A., Mølin, S., Tolker-Nielsen, T., Mol. Microbiol. 50, 1 (2003).Google Scholar
49.Nielsen, A.T., Tolker-Nielsen, T., Barken, K.B., Molin, S., Environ. Microbiol. 2, 1 (2000).Google Scholar