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Nanoparticle Embedded Nanofiber Synthesis and Evaluation of Usability on Biomedical Applications

Published online by Cambridge University Press:  19 February 2018

Dilek Çökeliler Serdaroğlu*
Affiliation:
Biomedical Engineering, Başkent University, Bağlıca Campus, 06790Ankara, Turkey
Hilal K. Korkusuz
Affiliation:
Biomedical Engineering, Başkent University, Bağlıca Campus, 06790Ankara, Turkey
Mine Karakaya
Affiliation:
Biomedical Engineering, Başkent University, Bağlıca Campus, 06790Ankara, Turkey
İlknur Dönmez
Affiliation:
Biomedical Engineering, Başkent University, Bağlıca Campus, 06790Ankara, Turkey
Mehmet A. Ünal
Affiliation:
Physics Engineering, Ankara University, 06100, Ankara, Turkey
Sundaram Gunasekaran
Affiliation:
Biological Systems Engineering, University of Wisconsin Madison, Madison, WI53760, U.S.A
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Abstract

When nanoparticles and nanofibers combined at the nanoscale, they could create new features in the material and therefore new areas of use. In this study, polyvinylpyrrolidone (PVP) nanofibers containing carbon nanoparticles produced by dense medium plasma technology have been fabricated via electrospinning technique for the first time, a new class of nanocomposite mat material has been prepared and evaluated for medical devices. A dense medium plasma technique is used for nanoparticles synthesis, which is novel, cost-efficient, and fast technology when is compared with other common nanoparticles synthesis techniques. Carbon based nanoparticles are synthesized from an arc sustained in benzene (purity, 99.5%) between iron electrodes by the lab-made dense medium plasma system. The study first mentions the production of nanoparticles by a pressure of 8 bar argon gas for glow discharge in a period of 9 seconds using a 0.5 cm electrode distance in a liquid environment (volume of benzene: 30 ml). Then, separated carbon nanoparticles are integrated with the PVP nanofibers produced by the electrospinning method. Processing parameters of PVP nanofibers containing carbon nanoparticle (nanocomposites) are optimized with various conditions such as polymer concentration: 7.8-8.0 %w/v, ratio of nanoparticle to polymer solution: 1-3.9 mg /ml, distance of electrode: 10-25 cm, processing time: 5-30 min. All samples are characterized by contact angle measurements, scanning electron microscopy and transmission electron microscopy. At the same time, electrical conductivity of nanocomposite mats are tested for foreseeing usage in biomedical application. Results showed that carbon nanoparticles have diameters in 25 ± 5.4 nm. New nanocomposite material production is proven by transmission electron microscopy. It is a super hydrophilic mat material (static contact angle is lower than 10°). According to the optimization of processing parameters, the diameters of nanocomposite fibers reach down to 150 ±75 nm., Nanocomposite mat resistance is found to be dramatically higher than that for the bare PVP nanofiber mat resistance. According to these results, usage in biomedical application of new material was discussed. It has a great potential to use as biocompatible, light, insulator new material.

Type
Articles
Copyright
Copyright © Materials Research Society 2018 

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References

REFERENCES

Vasita, R. and Katti, D.S., International Journal of Nanomedicine 1, 1530 (2006).Google Scholar
Huang, Z.M, Zhang, Y. Z., Kotaki, M., and Ramakrishna, S., Composites Science and Technology 63,22232253 (2003).Google Scholar
Li, W. J., Laurencin, C. T., Caterson, E. J., Tuan, R. S., and Ko, F. K., Journal of Biomedical Materials Research, P. A. 60, 613621 (2002).Google Scholar
Li, S., Lin, M. M., Toprak, M. S., Kim, D. K. and Muhammed, M., Nano Reviews 1, 52145232 (2010).CrossRefGoogle Scholar
Son, W. K., Youk, J. H., Park, W. H., Carbohydrate Polymers, 430434 (2006).Google Scholar
Subramanian, V., Wolf, E. E., and Kamat, P. V., Journal of the American Chemical Society 126, 49434950 (2004).CrossRefGoogle Scholar
Agarwal, S., Wendorff, J. H. and Greiner, A., Polymer 49, 56035621 (2008)Google Scholar
Teo, W. E., İnai, R. and Ramaksihna, S., Science and Technology of Advanced Materials 12, 119 (2011).Google Scholar
Barakat, N. A. M., Abadir, M.F., Sheikh, F. A., Kanjwal, M. A., Park, S. J., Kim, H. Y., Chemical Engineering Journal, 156, 487495 (2010).Google Scholar
Ma, Y., Manolache, S., Denes, F., Thamm, D, D.H., Kurzman, I.D., Vail, D.M., J. Biomater. Sci. Polymer Edn, 15(8), 10331049 (2004).Google Scholar
Afzali, M., Mostafavi, A., and Shamspur, T., Materials Science and Engineering, C 68, 789797. (2016).Google Scholar
Liu, Y., Huang, H., Wang, L., Cai, D., Liu, B., Wang, D., Li, Q., and Wang, T., Sensors and Actuators B: Chemical 223, 730737. (2016).Google Scholar
Deniz, A.E., Vural, H.A., Ortaç, B., and Uyar, T., Materials Letters 65, 29412943. (2011).Google Scholar
Quirós, J., Borges, J.P., Boltes, K., Rodea-Palomares, I., and Rosal, R., Journal of Hazardous Materials 299, 298305 (2015).Google Scholar
Tański, T., Matysiak, W., Krzemiński, Ł., Jarka, P., and Gołombek, K., Applied Surface Science 424, 184189 (2017).Google Scholar
Nasouri, K., Shoushtari, A.M, and Mojtahedi, M.R.M., Polymer Composites 38, 20262034 (2017).Google Scholar
Barzegar, F., Bello, A., Fabiane, M., Khamlich, S., Momodu, D., Taghizadeh, F., Dangbegnon, J., and Manyala, N., Journal of Physics and Chemistry of Solids 77, 139145 (2015).Google Scholar
Müller, F., Ferreira, C.A., Azambuja, D. S., Aleman, C., Armelin, E., Journal of Physical Chemistry 118, 11021112 (2014).Google Scholar