Hostname: page-component-8448b6f56d-tj2md Total loading time: 0 Render date: 2024-04-25T05:21:09.267Z Has data issue: false hasContentIssue false
  • English
  • Français

Micro-cellulose sponge from waste cotton as controlled-release Polyphenol carriers

Published online by Cambridge University Press:  27 June 2016

Chutimon Satirapipathkul  and
Pichet Dungsri
Chutimon Satirapipathkul*
Affiliation:
Chemical Engineering Research Unit for Value Adding of Bioresource, Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Phayathai Road, Phatumwan, Bangkok 10330, Thailand.
Pichet Dungsri
Affiliation:
Chemical Engineering Research Unit for Value Adding of Bioresource, Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Phayathai Road, Phatumwan, Bangkok 10330, Thailand.
*
*(Email: chutimon.s@chula.ac.th)
Get access

Abstract

Polyphenol in mango seed kernel extraction has been demonstrated to show benefits against skin disorders. In this study, micro-cellulose sponges (MCS) from waste cotton are used as the carrier for polyphenol to produce a controlled release system. Polyphenol loaded micro-cellulose sponges were produced by acid hydrolysis and a freeze drying method. The microparticles were characterized in terms of size and morphology, total polyphenol loading, and physical state of the encapsulated polyphenol. Polyphenol release from the microparticles was assessed by dissolution tests. The particles had spherical shapes with amorphous form. The controlled drug release was tested by using different polyphenol concentration. The results showed that the structure of micro-cellulose sponges, the media type and the solubility of the polyphenol influenced the polyphenol-release behavior. Since the release of the polyphenol is controlled by the structure and interactions between the microparticles and the cellulose matrix, modulation of the matrix formers enable a control of the drug release rate. These structures of micro-cellulose sponges can be very useful in many pharmaceutical micro-particle applications.

Keywords

absorptionbiomaterialchemical composition
Type
Articles
Information
MRS Advances , Volume 1 , Issue 36: Soft Materials and Biomaterials , 2016 , pp. 2545 - 2550
Copyright
Copyright © Materials Research Society 2016 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Entcheva, E., Bien, H., Yin, L., Chung, C.Y., Farrell, M., Kostov, Y., Biomaterials 25 (26), 5753–5762 (2004)CrossRefGoogle Scholar
Märtson, M., Viljanto, J., Hurme, T., Laippala, P., Saukko, P., Biomaterials 20 (21), 1989–1995(1999)Google Scholar
Rodríguez, K., Gatenholm, P., Renneckar, S., Cellulose 19 (5), 1583–1598 (2012)Google Scholar
Bledzki, A.K., Gassan, J., Prog. Polym. Sci. 24, 221 (1999)Google Scholar
Tingaut, P., Zimmermann, T., Sèbe, G., J. Mater. Chem. 22, 20105 (2012)CrossRefGoogle Scholar
Siro, I., Plackett, D., Cellulose 17, 459 (2010)Google Scholar
Chen, W., Yu, H., Li, Q., Liu, Y., Li, J., Soft Matter 7, 10360 (2011)Google Scholar
Gebald, C., Wurzbacher, J.A., Tingaut, P., Zimmermann, T., Steinfeld, A., Environ. Sci. Technol.45, 9101 (2011)CrossRefGoogle Scholar
Cervin, N.T., Aulin, C., Larsson, P.T., Wågberg, L., Cellulose 19, 1 (2011)Google Scholar
Sehaqui, H., Zhou, Q., Berglund, L.A., Compos. Sci.Technol 71, 1593 (2012)Google Scholar
Aulin, C., Netrval, J., Wågberg, L., Lindström, T., Soft Matter 6, 3298 (2010)Google Scholar
Eichhorn, S.J., Sampson, W.W., J R Soc Interface 7(45): 641–649 (2010)Google Scholar