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Magnesium-based Biodegradable Materials for Biomedical Applications

Published online by Cambridge University Press:  08 June 2018

Chaoxing Zhang
Affiliation:
Materials Science and Engineering Program, University of California at Riverside, 900 University Avenue, Riverside, CA92521, United States
Jiajia Lin
Affiliation:
Materials Science and Engineering Program, University of California at Riverside, 900 University Avenue, Riverside, CA92521, United States
Huinan Liu*
Affiliation:
Materials Science and Engineering Program, University of California at Riverside, 900 University Avenue, Riverside, CA92521, United States Department of Bioengineering, University of California at Riverside, 900 University Avenue, Riverside, CA92521, United States Biomedical Sciences Program, School of Medicine, University of California at Riverside, 900 University Avenue, Riverside, CA92521, United States Stem Cell Center, University of California at Riverside, 900 University Avenue, Riverside, CA92521, USA
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Abstract

Magnesium (Mg)-based biomaterials have attracted increasing attention in biomedical applications, such as orthopaedic, cardiovascular, urological, and neural applications because of the biocompatibility, biodegradability, antibacterial properties, and excellent mechanical properties. However, rapid degradation of Mg is the major concern for many clinical applications. Alloying Mg with other elements and engineering proper surfaces are the two approaches to control the degradation of Mg-based biomaterials. Our lab has investigated several classes of Mg-based biodegradable alloys and various surface treatment methods for medical implant and device applications. This mini-review highlights key research progress on Mg-based biomaterials and suggests future directions for Mg-based biomaterials.

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Copyright
Copyright © Materials Research Society 2018 

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