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Effect of asymptomatic carotid artery disease on cognitive outcome after cardiopulmonary bypass

Published online by Cambridge University Press:  26 February 2009

Guy Vingerhoets
Affiliation:
Department of Psychiatry and Neuropsychology, University Gent
Guido van Nooten
Affiliation:
Center for Cardiac Surgery, University Gent
Constantin Jannes
Affiliation:
Department of Psychiatry and Neuropsychology, University Gent

Abstract

This prospective study reinvestigates the effect of asymptomatic carotid artery disease on the cognitive outcome after cardiopulmonary bypass (CPB) (Harrison et al., 1989). Patients (N = 104) scheduled for cardiac surgery using CPB were classified in one of two groups based on the results of a preoperative duplex B mode Dopplcr scan of the internal carotid arteries. All patients received a neuropsychological examination before surgery, 8 days after surgery, and 6 months after surgery (n = 79). When group data are considered, patients showed evidence of selective cognitive dysfunction early after surgery. These dysfunctions were resolved by the sixth postoperative month. We found no indications that the presence of asymptomatic carotid artery disease increased the incidence of cognitive disturbances after CPB or differentially affected the postoperative performance. We conclude that mild to moderate asymptomatic carotid artery disease does not appear to play a major role in the genesis of postoperative neuropsychological sequelae. (JINS, 1996,2, 236–239.)

Type
Research Article
Copyright
Copyright © The International Neuropsychological Society 1996

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