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Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and RapidArc in low grade mucoepidermoid carcinoma of the salivary gland: a single institutional experience

Published online by Cambridge University Press:  15 October 2020

Amna Ghaffar
Affiliation:
Department of Medical Physics, Shaukat Khannum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
Muhammad Yousaf
Affiliation:
Department of Medical Physics, Shaukat Khannum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
Sajid Anees Minhas
Affiliation:
Department of Medical Physics, Shaukat Khannum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
Rizwan Hameed
Affiliation:
Department of Medical Physics, Shaukat Khannum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
Umair Zafar
Affiliation:
Department of Medical Physics, Shaukat Khannum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
Khalid Iqbal
Affiliation:
Department of Medical Physics, Shaukat Khannum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

Abstract

Purpose:

To report a single-institution experience of intensity-modulated radiotherapy (IMRT) and RapidArc treatment plans for the patients treated with low grade mucoepidermoid carcinoma (MEC) of the salivary gland while sparing the organs at risk (OARs) within tolerance limits.

Material and Methods:

Twenty-five patients with MEC were selected to develop and analyse the treatment plans using both of the techniques. Dose distributions were calculated using Eclipse treatment planning system (Varian Medical Systems, Palo Alto, CA). Plans were generated to deliver the dose of 6000 cGy in 30 fractions. For IMRT, seven angle plans were used and for RapidArc, two half arcs were used with the same 6 MV photon beam. Quality of treatment plans was evaluated by using parameters such as, coverage, conformity index (CI), homogeneity index (HI), gradient index (GI), unified dosimetry index (UDI), dose volume histogram, delivery time and OARs sparing for IMRT and RapidArc plans.

Results:

The analysis revealed that IMRT and RapidArc coverages are 0·90 and 0·94, respectively; CIs are 1·15 and 1·10, respectively; HIs are 1·12 and 1·07, respectively; GIs are 0·94 and 0·98, respectively. Average UDI values for RapidArc and IMRT are 1·09 and 1·11, respectively. Integral dose comparison shows better OAR sparing for RapidArc. RapidArc plans have the shorter beam on time (45%) in comparison with IMRT plans.

Conclusion:

Planning constraints were achieved in both techniques. However, RapidArc showed better quality treatment plan, OARs sparing and shorter delivery time as compared to IMRT.

Type
Original Article
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and RapidArc in low grade mucoepidermoid carcinoma of the salivary gland: a single institutional experience
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