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Paediatric aneurysmal bone cysts of the head and neck

Published online by Cambridge University Press:  02 September 2008

B G Fennessy*
Affiliation:
Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
S O Vargas
Affiliation:
Department of Pathology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
M V Silvera
Affiliation:
Department of Radiology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
L A Ohlms
Affiliation:
Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
T J McGill
Affiliation:
Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
G B Healy
Affiliation:
Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
R Rahbar
Affiliation:
Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
*
Address for correspondence: Mr Brendan Fennessy, c/o Dept of Otolaryngology and Communication Enhancement, Children's Hospital Boston, South Infirmary and Victoria Hospital, Cork City, Ireland. Fax: 00 1 353 1 824 9610 E-mail: brendanfennessy@yahoo.com

Abstract

Objective:

To provide an up to date review of the literature on aneurysmal bone cysts, including their diagnosis, pathology, pathophysiology, radiology and management.

Method:

Retrospective review of six cases over a 15-year period.

Results:

Six patients (age range, eight months to 17 years; mean, 9.6 years) presented with an aneurysmal bone cyst in the mandible (n = 3), maxilla (n = 2) or occipital soft tissue (n = 1). Each patient underwent primary excision, with one subsequent recurrence.

Conclusion:

Aneurysmal bone cysts are benign but locally destructive entities which may occasionally present to otolaryngologists, since they can involve the head and neck region, in particular the mandible.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 2008

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References

1 Rosenberg, AE, Nielsen, GP, Fletcher, JA. Aneurysmal bone cyst. In: Fletcher, CDM, Unni, KK, Mertens, F, eds. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press, 2002;338–9Google Scholar
2 Hamilton, HB, Voorhies, RM. Tumours of the skull. In: Wilkins, RH, Rengachary, SS, eds. Neurosurgery. New York: McGraw-Hill, 1996;2:1503–28Google Scholar
3 Barnes, L. Surgical Pathology of the Head and Neck. New York: Marcel Dekker, 2001;1164–9Google Scholar
4 Kaffe, I, Naor, H, Calderon, S, Buchner, A. Radiological and clinical features of aneurysmal bone cyst of the jaws. Dentomaxillary Radiol 1999;28:167–72CrossRefGoogle ScholarPubMed
5 Martinez, V, Sessone, HA. Aneurysmal bone cyst. A review of 123 cases including primary lesions and those secondary to other bone pathology. Cancer 1988;61:2291–3043.0.CO;2-V>CrossRefGoogle ScholarPubMed
6 Nielsen, GP, Fletcher, CDM, Smith, MA, Rybak, L, Rosenberg, A. Soft tissue aneurysmal bone cyst: a clinicopathologic study of five cases. Am J Surg Pathol 2002;26:64–9CrossRefGoogle ScholarPubMed
7 Struthers, PJ, Shear, M. Aneurysmal bone cyst of the jaws. I. Clinicopathological features. Int J Oral Surg 1984;13:8591Google Scholar
8 Szendroi, M, Cser, I, Konya, A, Renyi-Vamos, A. Aneurysmal bone cyst: a review of 52 primary and 16 secondary cases. Arch Orthop Trauma Surg 1992;111:318–22Google Scholar
9 David, K, Horvath, V, Horvath, A, Iles, T. Aneurysmal bone cyst of the occipital bone: case report. Surg Neurol 1993;40:332–5Google Scholar
10 Petrik, PK, Findlay, JM, Sherlock, RA. Aneurysmal cyst, bone type, primary in an artery. Am J Surg Pathol 1993;17:1062–6CrossRefGoogle Scholar
11 Helliwel, TR. Pathology of Bone and Joint Neoplasms. Philadelphia: Saunders, 1999;339Google Scholar
12 Cottalorda, J, Bourella, S. Current treatments of primary aneurysmal bone cysts. J Pediatr Orthop 2006;15:155–67CrossRefGoogle ScholarPubMed
13 Mirra, JM. Cyst and cyst-like lesions of bone. In: Mirra, JM, ed. Bone Tumours: Clinical, Radiologic and Pathologic Correlations. Philadelphia: Lea & Febiger, 1989;2:1267–311Google Scholar
14 Simon, MA, Springfield, DS. Aneurysmal bone cyst. In: Surgery for Bone and Soft Tissue Tumors. Philadelphia: Lippincott-Raven, 1997;194–6Google Scholar
15 Fechner, RE, Mills, SE. Tumors of the Bones and Joints, Atlas of Tumor Pathology. Bethesda: Armed Forces Institute of Pathology, Washington DC, under the auspices of Universities Associated for Research and Education in Pathology Inc., Bethesda, Maryland., 1993;253–8Google Scholar
16 Kransdorf, MJ, Sweet, DE. Aneurysmal bone cyst: concept, controversy, clinical presentation, and imaging. AJR Am J Roentgenol 1995;164:573–80CrossRefGoogle ScholarPubMed
17 Dormans, JP, Hanna, BG, Johnston, DR, Khurana, JS. Surgical treatment and recurrence rate of aneurysmal bone cysts in children. Clin Orthop 2004;421:205–11CrossRefGoogle Scholar
18 Schajowicz, F. Aneurysmal bone cyst. In: Schajowicz, F, ed. Tumors and Tumor like Lesions of Bone: Pathology, Radiology and Treatment. New York: Springer-Verlag, 1994;514–30Google Scholar
19 Calliauw, L, Roels, H, Caemaert, J. Aneurysmal bone cysts in the cranial vault and base of skull. Surg Neurol 1985;23:193–8Google Scholar
20 Lindbom, A, Soderberg, H, Spjut, HJ, Sunnqvist, O. Angiography of aneurysmal bone cyst. Acta Radiol 1961;55:1216Google Scholar
21 Enneking, WF. Musculoskeletal Tumour Surgery. New York: Churchill Livingstone, 1983Google Scholar
22 Casadei, R, Ruggeri, P, Moscato, M, Ferraro, A, Picci, P. Aneurysmal bone cyst and giant cell tumor of the foot. Foot Ankle Int 1996;17:487–95CrossRefGoogle ScholarPubMed
23 Kransdorf, MJ, Sweet, DE. Aneurysmal bone cyst: concept, controversy, clinical presentation and imaging. Am J Clin Path 1995;164:573–80Google Scholar
24 Marcove, RC, Sheth, DS, Takemoto, S, Healey, JH. The treatment of aneurysmal bone cyst. Clin Orthop 1995;311:157–63Google Scholar
25 Brindley, GW, Greene, JF Jr, Frankel, LS. Case reports: malignant transformation of aneurysmal bone cysts. Clin Orthop Relat Res 2005;438:282–7CrossRefGoogle ScholarPubMed
26 deMello, DE, Archer, CR, Blair, JD. Ethmoidal fibro-osseous lesion in a child. Diagnostic and therapeutic problems. Am J Surg Pathol 1980;4:595601CrossRefGoogle Scholar
27 Panoutsakopoulos, G, Pandis, N, Kyriazogloe, I, Gustafson, P, Mertens, F, Mandahl, N. Recurrent t(16;17)(q22;p13) in aneurysmal bone cysts. Genes Chromosomes Cancer 1999;26:265–63.0.CO;2-#>CrossRefGoogle Scholar
28 Oliveira, AM, His, BL, Weremowicz, S, Rosenberg, AE, Dal Cin, P, Joeseph, N et al. USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst. Cancer Res 2004;64:1920–3CrossRefGoogle ScholarPubMed
29 Dal Cin, P, Kozakewich, HP, Goumnerova, L, Mankin, HJ, Rosenberg, AE, Fletcher, JA. Variant translocations involving 16q22 and 17p13 in solid variant and extraosseous forms of aneurysmal bone cyst. Genes Chromosomes Cancer 2000;28:233–43.0.CO;2-H>CrossRefGoogle ScholarPubMed
30 Gleason, BC, Kleinman, PK, Debelenko, LV, Rahbar, R, Gebhardt, MC, Perez-Atayde, AR. Novel karyotypes in giant cell-rich lesions of bone. Am J Surg Pathol 2007;31:926–32Google Scholar
31 Docquier, PL, Delloye, C. Treatment of aneurysmal bone cysts by introduction of demineralised bone and autogenous bone marrow. J Bone Joint Surg Am 2005;87:2253–8Google ScholarPubMed
32 Glorion, C, Brunelle, F, Ghazai, D, Chotel, F. Treatment of aneurysmal bone cysts in children and adolescents with a neat alcohol solution. Preliminary results about 7 cases [abstract]. 34th Congress of French Osseous Tumors Society; 2004:132137Google Scholar
33 Szendroi, M, Antal, I, Liszka, GY, Konya, A. Calcitonin therapy of aneurysmal bone cysts. J Cancer Res Clin Oncol 1992;119:61–5CrossRefGoogle ScholarPubMed
34 Cottalorda, J, Kohler, R, Chotel, F, de Gauzy, JS, Lefort, G, Louahem, D et al. Recurrence of aneurysmal bone cysts in young children: a multicentre study. J Pediatr Orthop B 2005;14:212–18CrossRefGoogle ScholarPubMed
35 Falappa, P, Fassaria, FM, Fanelli, A, Genovese, E, Ascani, E, Crostelli, M et al. Aneurysmal bone cysts: treatment with direct percutaneous Ethibloc injection: long term results. Cardiovasc Intervent Radiol 2002;25:282–90CrossRefGoogle ScholarPubMed
36 Topouchian, V, Mazda, K, Hamze, B, Laredo, JD, Pennecot, GF. Aneurysmal bone cysts in children: complications of fibrosing agent injection. Radiology 2004;232:522–6CrossRefGoogle ScholarPubMed
37 Green, JA, Bellemore, MC, Marsden, FW. Embolisation in the treatment of aneurysmal bone cysts. J Pediatr Orthop 1997;17:440–3CrossRefGoogle ScholarPubMed
38 Cottalorda, J, Bourelle, S. Current treatments of primary aneurysmal bone cysts. J Pediatr Orthop 2006;15:155–67CrossRefGoogle ScholarPubMed
39 Schreuder, HWB, Veth, RPH, Pruszczynski, M, Lemmens, JA, Koops, HS, Molenaar, WM. Aneurysmal bone cyst treated by currettage, cryotherapy and bone grafting. J Bone Joint Surg Br 1997;79:20–5CrossRefGoogle Scholar
40 Marcove, RC, Sheth, DS, Takemoto, S, Healey, JH. The treatment of aneurysmal bone cyst. Clin Orthop 1995; 311: 157163Google Scholar
41 Ozaki, T, Hillmann, A, Linder, N, Winkelmann, W. Cementation of primary aneurysmal bone cysts. Clin Orthop 1997;337:240–8CrossRefGoogle Scholar
42 Kumar, P, Singh, S, Phadke, RV, Diwakar, H, Agarawal, T, Jain, M et al. Role of radiotherapy in a recurrent aneurysmal bone cyst of the temporal bone: case report. Neurosurgery 2006;58:E584CrossRefGoogle Scholar
43 Fajardo, LF. The pathology of ionizing radiation as defined by morphologic patterns. Acta Oncol 2005;44:1322CrossRefGoogle ScholarPubMed
44 Mendenhall, WM, Zlotecki, RA, Gibbs, CP, Reith, JD, Scarborough, MT, Mendenhall, NP. Aneurysmal bone cyst. Am J Clin Oncol 2006;29:311–15Google Scholar
45 Cawson, RA, Binnie, WH, Speight, P, Wright, JM. Lucas' Pathology of Tumours of the Oral Tissues. London: Churchill-Livingstone, 1998;155–7Google Scholar