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Hearing recovery from deafness caused by bromate intoxication

Published online by Cambridge University Press:  16 November 2018

J Suzuki*
Affiliation:
Department of Otolaryngology, Iwaki Kyoritsu General Hospital, Japan Department of Otolaryngology – Head and Neck Surgery, Tohoku University School of Medicine, Japan
Y Takanashi
Affiliation:
Department of Otolaryngology, Iwaki Kyoritsu General Hospital, Japan Department of Otolaryngology – Head and Neck Surgery, Tohoku University School of Medicine, Japan
A Koyama
Affiliation:
Emergency Center, Iwaki Kyoritsu General Hospital, Japan
Y Katori
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Tohoku University School of Medicine, Japan
*
Author for correspondence: Dr J Suzuki, Department of Otolaryngology – Head and Neck Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan E-mail: j_suzuki1212@orl.med.tohoku.ac.jp Fax: +81 22 717 7307

Abstract

Objectives

Sodium bromate is a strong oxidant, and bromate intoxication can cause irreversible severe-to-profound sensorineural hearing loss. This paper reports the first case in the English literature of bromate-induced hearing loss with hearing recovery measured by formal audiological assessment.

Case report

A 72-year-old woman was admitted to hospital with complaints of profound hearing loss, nausea, diarrhoea and anuria after bromate ingestion in a suicide attempt. On admission, pure tone audiometry and auditory brainstem responses showed profound bilateral deafness. Under the diagnosis of bromate-induced acute renal failure and sensorineural hearing loss, continuous haemodiafiltration was performed. When dialysis was discontinued, pure tone audiometry and auditory brainstem responses showed partial threshold recovery from profound deafness.

Conclusion

Severe-to-profound sensorineural hearing loss is a common symptom of bromate intoxication. Bromate-induced hearing loss may be partially treated, and early application of continuous haemodiafiltration might be useful as a treatment for this intractable condition.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr J Suzuki takes responsibility for the integrity of the content of the paper

References

1Matsumoto, I, Morizono, T, Paparella, MM. Hearing loss following potassium bromate: two case reports. Otolaryngol Head Neck Surg (1979) 1980;88:625–9Google Scholar
2Wang, V, Lin, KP, Tsai, CP, Kao, KP. Bromate intoxication with polyneuropathy. J Neurol Neurosurg Psychiatry 1995;58:516–17Google Scholar
3Sashiyama, H, Irie, Y, Ohtake, Y, Nakajima, K, Yoshida, H, Sakai, T et al. Acute renal failure and hearing loss due to sodium bromate poisoning: a case report and review of the literature. Clin Nephrol 2002;58:455–7Google Scholar
4Uchida, HA, Sugiyama, H, Kanehisa, S, Harada, K, Fujiwara, K, Ono, T et al. An elderly patient with severe acute renal failure due to sodium bromate intoxication. Intern Med 2006;45:151–4Google Scholar
5Ryu, DH, Jang, KA, Kim, SM, Park, JW, Do, JY, Yoon, KW. Acute kidney injury due to sodium bromate intoxication: a report of two cases. Korean J Intern Med 2011;26:463–5Google Scholar
6Eom, TH, Lee, S, Cho, HH, Cho, YB. A case of cochlear implantation in bromate-induced bilateral sudden deafness. J Audiol Otol 2015;19:51–3Google Scholar
7Campbell, KC. Bromate-induced ototoxicity. Toxicology 2006;221:205–11Google Scholar
8Gradus, D, Rhoads, M, Bergstrom, LB, Jordan, SC. Acute bromate poisoning associated with renal failure and deafness presenting as hemolytic uremic syndrome. Am J Nephrol 1984;4:188–91Google Scholar
9Asakuma, S, Snow, JB Jr. Effects of sodium bromate and nitrogen mustard on endocochlear DC potential and electrical resistance of the cochlear partition in normal and kanamycin-treated guinea pigs. Surg Forum 1978;29:573–5Google Scholar
10Muratsuka, Y, Ueda, H, Konishi, T. Effects of sodium bromate on ionic concentrations and osmolalities of the cochlear fluids in guinea pigs. Hear Res 1989;39:241–9Google Scholar
11Tojima, I, Suzuki, M, Hanamitsu, M, Fukui, J, Sakurai, H, Shimizu, T. A case of hearing loss due to potassium bromate [in Japanese]. Practica Oto-Rhino-Laryngologica 2008;101:257–60Google Scholar
12Oda, S, Hirasawa, H, Shiga, H, Nakanishi, K, Matsuda, K, Nakamura, M. Continuous hemofiltration/hemodiafiltration in critical care. Ther Apher 2002;6:193–8Google Scholar
13Tono, T, Ushisako, Y, Morimitsu, T, Takenaka, M. Cochlear implants in deafened patients due to potassium bromate poisoning. Adv Otorhinolaryngol 1997;52:315–17Google Scholar