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Frontal sinus obliteration with beta-tricalcium phosphate putty: case series with long-term radiological follow up

Published online by Cambridge University Press:  20 June 2022

P Moore Open the ORCID record for P Moore [Opens in a new window] ,
J K T Kam ,
M Castle-Kirszbaum ,
D Tan ,
S Wreghitt ,
S Lee  and
C A Gonzalvo
P Moore*
Affiliation:
Department of ENT, Head and Neck Surgery, Austin Health, Melbourne, Australia
J K T Kam
Affiliation:
Department of Neurosurgery, Monash Health, Melbourne, Australia
M Castle-Kirszbaum
Affiliation:
Department of Neurosurgery, Monash Health, Melbourne, Australia
D Tan
Affiliation:
Department of Neurosurgery, Monash Health, Melbourne, Australia
S Wreghitt
Affiliation:
Department of Neurosurgery, Austin Health, Melbourne, Australia
S Lee
Affiliation:
Department of ENT, Head and Neck Surgery, Austin Health, Melbourne, Australia
C A Gonzalvo
Affiliation:
Department of Neurosurgery, Austin Health, Melbourne, Australia
*
Author for correspondence: Dr Phillip Moore, Department of ENT, Head and Neck Surgery, Austin Health, 145 Studley Rd, Heidelberg, Victoria, Australia 3084 E-mail: philljmoore@gmail.com
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Abstract

Objectives

Frontal sinus obliteration is often performed using fat, autologous bone or a range of synthetic materials. This paper reports the long-term clinical and radiological outcomes of frontal sinus obliteration using beta-tricalcium phosphate putty.

Methods

A retrospective audit was performed of patients who underwent frontal sinus obliteration with beta-tricalcium phosphate putty. Patient-, disease- and procedure-related data were collected. Pre- and post-operative computed tomography scans were reviewed to assess bone integration.

Results

Four patients underwent frontal sinus obliteration using beta-tricalcium phosphate putty for treatment of a cerebrospinal leak, mucocele and recalcitrant frontal sinusitis. All patients had disease resolution, with no intra- or post-operative complications reported in the 16.5-month follow up. Post-operative computed tomography scans confirmed native bone obliteration of the frontonasal ducts in all patients.

Conclusion

Beta-tricalcium phosphate putty is a safe and effective option for bone obliteration of the frontal sinus in a range of pathologies, including cerebrospinal fluid leak.

Keywords

Frontal SinusCerebrospinal Fluid LeakFrontal SinusitisMucoceleBone Substitute
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 137 , Issue 2 , February 2023 , pp. 163 - 168
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Dr P Moore takes responsibility for the integrity of the content of the paper

This paper was presented at the 8th World Federation of Skull Base Societies Meeting, 22–27 March 2022, Rio de Janeiro, Brazil.

References

Dai, LY, Jiang, LS. Single-level instrumented posterolateral fusion of lumbar spine with beta-tricalcium phosphate versus autograft: a prospective, randomized study with 3-year follow-up. Spine (Phila Pa 1976) 2008;33:1299–30410.1097/BRS.0b013e3181732a8eCrossRefGoogle ScholarPubMed
Gunzburg, R, Szpalski, M. Use of a novel beta-tricalcium phosphate-based bone void filler as a graft extender in spinal fusion surgeries. Orthopedics 2002;25:s591–5CrossRefGoogle ScholarPubMed
Epstein, NE. Beta tricalcium phosphate: observation of use in 100 posterolateral lumbar instrumented fusions. Spine J 2009;9:630–8CrossRefGoogle ScholarPubMed
Galois, L, Mainard, D, Delagoutte, JP. Beta-tricalcium phosphate ceramic as a bone substitute in orthopaedic surgery. Int Orthop 2002;26:109–15Google ScholarPubMed
Guillaume, B. Filling bone defects with β-TCP in maxillofacial surgery: a review. Morphologie 2017;101:113–19CrossRefGoogle ScholarPubMed
Bohner, M, Santoni, BLG, Dobelin, N. Beta-tricalcium phosphate for bone substitution: synthesis and properties. Acta Biomater 2020;113:23–41CrossRefGoogle ScholarPubMed
Elahi, MM, Vanduzer, S, Spears, J, Gibson, J, Mitra, A. Frontal sinus obliteration with beta-tricalcium phosphate. J Craniofac Surg 2004;15:967–70CrossRefGoogle ScholarPubMed
Andratschke, M, Hagedorn, H. First results of frontal sinus obliteration with a synthetic, resorbable and osteoconductive bone graft of β-tricalcium phosphate. J Laryngol Otol 2017;131:534–40CrossRefGoogle Scholar
Hardy, JM, Montgomery, WW. Osteoplastic frontal sinusotomy: an analysis of 250 operations. Ann Otol Rhinol Laryngol 1976;85:523–32CrossRefGoogle ScholarPubMed
Kang, GC, Sng, KW, Tay, AG. Modified technique for frontal sinus obliteration using calvarial bone and Tisseel glue. J Craniofac Surg 2009;20:528–31CrossRefGoogle ScholarPubMed
Vironneau, P, Coste, A, Pruliere-Escabasse, V. Frontal sinus obliteration with autologous calvarial bone graft: indications and results. Eur Arch Otorhinolaryngol 2014;271:2957–62CrossRefGoogle ScholarPubMed
Friedman, CD, Costantino, PD, Synderman, CH, Chow, LC, Takagi, S. Reconstruction of the frontal sinus and frontofacial skeleton with hydroxyapatite cement. Arch Facial Plast Surg 2000;2:124–9CrossRefGoogle ScholarPubMed
Petruzzelli, GJ, Stankiewicz, JA. Frontal sinus obliteration with hydroxyapatite cement. Laryngoscope 2002;112:32–6CrossRefGoogle ScholarPubMed
Taghizadeh, F, Kromer, A, Laedrach, K. Evaluation of hydroxyapatite cement for frontal sinus obliteration after mucocele resection. Arch Facial Plast Surg 2006;8:416–22CrossRefGoogle ScholarPubMed
Demir, B. Acrylic bone cement with Tutopatch for frontal sinus obliteration. J Laryngol Otol 2022;136:329–32CrossRefGoogle ScholarPubMed
Peltola, M, Aitasalo, K, Suonpaa, J, Varpula, M, Yli-Urpo, A. Bioactive glass S53P4 in frontal sinus obliteration: a long-term clinical experience. Head Neck 2006;28:834–41CrossRefGoogle ScholarPubMed
Zijderveld, SA, Zerbo, IR, van den Bergh, JP, Schulten, EA, ten Bruggenkate, CM. Maxillary sinus floor augmentation using a beta-tricalcium phosphate (Cerasorb) alone compared to autogenous bone grafts. Int J Oral Maxillofac Implants 2005;20:432–40Google ScholarPubMed
Gorla, LF, Spin-Neto, R, Boos, FB, Pereira Rdos, S, Garcia-Junior, IR, Hochuli-Vieira, E. Use of autogenous bone and beta-tricalcium phosphate in maxillary sinus lifting: a prospective, randomized, volumetric computed tomography study. Int J Oral Maxillofac Surg 2015;44:1486–9110.1016/j.ijom.2015.07.003CrossRefGoogle ScholarPubMed
Uckan, S, Deniz, K, Dayangac, E, Araz, K, Ozdemir, BH. Early implant survival in posterior maxilla with or without beta-tricalcium phosphate sinus floor graft. J Oral Maxillofac Surg 2010;68:1642–5CrossRefGoogle ScholarPubMed
Hirata, M, Murata, H, Takeshita, H, Sakabe, T, Tsuji, Y, Kubo, T. Use of purified beta-tricalcium phosphate for filling defects after curettage of benign bone tumours. Int Orthop 2006;30:510–13CrossRefGoogle ScholarPubMed
Jeon, JW, Jang, S, Ro, DH, Lee, MC, Han, HS. Faster bone union progression and less sclerosis at the osteotomy margin after medial opening-wedge high tibial osteotomy using highly porous beta-tricalcium phosphate granules versus allogeneic bone chips: a matched case-control study. Knee 2021;29:33–41CrossRefGoogle ScholarPubMed
Higuchi, H, Kobayashi, A, Ikeda, K, Hatayama, K, Yanagisawa, S, Kato, K. Efficacy of beta-tricalcium phosphate graft into the bone defects after bone-patellar tendon-bone anterior cruciate ligament reconstruction. J Knee Surg 2017;30:467–73Google ScholarPubMed