Hostname: page-component-76fb5796d-skm99 Total loading time: 0 Render date: 2024-04-25T11:37:40.459Z Has data issue: false hasContentIssue false
  • English
  • Français

Distribution of lymecycline in interstitial fluid and paranasal sinus mucosa. An experimental and clinical study

Published online by Cambridge University Press:  29 June 2007

S. E. Holm ,
A-M. Bergholm ,
C. Ekedahl  and
K. Lundin
S. E. Holm
Affiliation:
Department of Clinical Bacteriology, University of Umeå, Umeå, Sweden.
A-M. Bergholm
Affiliation:
Department of Clinical Bacteriology, University of Umeå, Umeå, Sweden.
C. Ekedahl
Affiliation:
Department of Oto-Rhino-Laryngology, Kärnsjukhuset, Skövde, Sweden.
K. Lundin
Affiliation:
Department of Oto-Rhino-Laryngology, Centrallasarettet, Mölndal, Sweden.
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 97 , Issue 1 , January 1983 , pp. 59 - 64
Copyright
Copyright © JLO (1984) Limited 1983

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Axelsson, A. and Brorsson, J.-E. (1974) The concentration of antibiotics in sinus secretions. Ampicillin, Cephradine and Erythromycine estolate. Annals of Otolaryngology, 83: 323.Google Scholar
Barza, M., Samuelson, T. and Weinstein, L. (1974) Penetration of antibiotics into fibrin loci in vivo. II. Comparison of nine antibiotics: Effect of dose and degree of protein binding. Journal of Infectious Diseases, 129: 66–72.CrossRefGoogle ScholarPubMed
Brorsson, J.-E., Roupe, G. and Seeberg, S. (1972) Tetracycline-resistant β-haemolytic streptococci in dermatological patients. British Journal of Dermatology, 86: 449.Google Scholar
Chisholm, G. D. (1978) The tissue cage model in the distribution of antibacterial agents. Scandinavian Journal of Infectious Diseases, Supplement 14: 118–124.Google ScholarPubMed
Chisholm, G. D., Waterworth, P. M., Calnan, J. S. and Garrard, L. P. (1973) Concentration of antibacterial agents in interstitial tissue fluid. British Medical Journal 1: 569–573.CrossRefGoogle ScholarPubMed
Craig, W. A. and Suh, B. (1978) Theory and Practical impact of binding of antimicrobials to serum proteins and tissue. Scandinavian Journal of Infectious Diseases, Supplement 14: 92–99.Google ScholarPubMed
Dornbusch, K., Nord, C.-E. and Olsson, B. (1975) Antibiotic susceptibility testing of anaerobic bacteria by the standardized disc diffusion method with special reference to Bacteroides fragilis. Scandinavian Journal of Infectious Diseases, 7: 59.CrossRefGoogle ScholarPubMed
Ekedahi, C., Holm, S. E. and Bergholm, A.-M. (1978) Penetration of antibiotics into the normal and diseased maxillary sinus mucosa. Scandinavian Journal of Infectious Diseases, Supplement 14: 279–284.Google Scholar
Ekedahi, C., Holm, S. E., Jeppson, P.-H., Lindström, J., Ludwig, C. and Bergholm, A.-M. (1981a) Concentration of Phenoxymethyl penicillin (PcV) in the mucous membrane of maxillary sinus in patients with and without signs of sinusitis. Acta Otolaryngologica, 92: 371–377.CrossRefGoogle Scholar
Ekedahl, C., Holm, S. E., Jeppson, P.-H., Lindström, J., Ludwig, C. and Berholm, A.-M. (1981b) Active phenoxymethyl penicillin in the mucous membranes of the oral bucca and maxillary sinus and in implanted diffusion chambers in rabbits. Acta Otolaryngologica, 92: 151–155.CrossRefGoogle ScholarPubMed
Holm, S. E., Ekedahl, C. and Bergholm, A.-M. (1978) Comparison of antibiotic assays using different experimental models and their possible clinical significance. Scandinavian Journal of Infectious Diseases, Supplement 14: 214–220.Google ScholarPubMed
Jeppesen, F. and Illum, P. (1972) Concentration of ampicillin in antral mucosa following administration of ampicillin sodium and pivampicillin. Acta Otolaryngologica, 73: 428.CrossRefGoogle ScholarPubMed
Jokinen, K. and Raunio, V. (1975) Penetration of axidocillin into the secretion and tissues in chronic maxillary sinusitis and tonsillitis. Acta Otolaryngologica, 79: 460.CrossRefGoogle ScholarPubMed
Kahlmeter, G. and Kamme, C. (1972) Tetracycline-resistant group A Streptococci and pneumococci. Scandinavia Journal of Infectious Diseases, 4: 193–196.CrossRefGoogle Scholar
Kaplan, I. M., McCracken, G. H. and Snyder, E. (1973) Influence of methodology upon apparent concentrations of antibiotics in tissue. Antimicrobial Agents and Chemotherapy, 3: 143–146.CrossRefGoogle ScholarPubMed
Kornguth, M. L. and Kunin, C. M. (1976) Binding of antibiotics to the human intracellular erythrocyte proteins hemoglobin and carbonic anhydrase. Journal of Infectious Diseases. 133: 185.CrossRefGoogle Scholar
Kunin, C. M. (1970) Binding of antibiotics to tissue homogenates. Journal of Infectious Diseases, 121: 55.CrossRefGoogle ScholarPubMed
Lundberg, Ch., Malmborg, A.-S. and Ivemark, B. I. (1974) Antibiotic concentrations in relation to structural changes in maxillary sinus mucosa following intramuscular or peroral treatment. Scandinavian Journal of Infectious Diseases, 6: 187.CrossRefGoogle ScholarPubMed