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Association between socioeconomic indicators and geographic distribution of vestibular schwannomas in West Scotland: a 15-year review

Published online by Cambridge University Press:  03 December 2020

L Caulley ,
M Sawada ,
E Crighton ,
M Khoury  and
G Kontorinis
L Caulley
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, University of Ottawa, Canada Department of Epidemiology, Erasmus University Medical Center Rotterdam, The Netherlands Ottawa Hospital Research Institute, Canada
M Sawada
Affiliation:
Department of Geography, Environment and Geomatics, University of Ottawa, Canada
E Crighton
Affiliation:
Department of Geography, Environment and Geomatics, University of Ottawa, Canada
M Khoury
Affiliation:
Department of Undergraduate Medicine, University of Ottawa, Canada
G Kontorinis*
Affiliation:
Department of Otolaryngology–Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK
*
Author for correspondence: Dr G Kontorinis, Department of Otolaryngology – Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK E-mail: gkontorinis@gmail.com
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Abstract

Objective

Socioeconomic risk factors may contribute to geographic variation in diseases, but studies are limited due to lack of large available cohorts.

Method

A geographic analysis was performed of the association between socioeconomic risk factors and the distribution of vestibular schwannomas in adults diagnosed with sporadic vestibular schwannomas through the National Health Services in the West of Scotland from 2000 to 2015.

Results

A total of 511 sporadic vestibular schwannomas were identified in a population of over 3.1 million. Prevalence of vestibular schwannomas were lowest in cases with good health (–0.64, 95 per cent confidence interval: –0.93,–0.38; p = 0.002) and level 1 qualifications (–0.562, 95 per cent confidence interval: –0.882 to –0.26; p = 0.01). However, these risk factors did not demonstrate consistent linearity of correlations. Prevalence was lower in people originating from European Union accession countries from April 2001 to March 2011 (–0.63, 95 per cent confidence interval: –0.84 to –0.43; p = 0.002). No correlation between distribution of vestibular schwannomas and socioeconomic risk factors met our threshold criteria (± 0.7).

Conclusion

This study demonstrated that there is little variation in distribution of vestibular schwannomas by socioeconomic risk factors.

Keywords

Neuroma, AcousticSkull Base NeoplasmsSocioeconomic FactorsPrevalenceScotlandRisk Factors
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 11 , November 2020 , pp. 942 - 950
Copyright
Copyright © The Author(s), 2020. Published by Cambridge University Press

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Footnotes

Dr G Kontorinis takes responsibility for the integrity of the content of the paper

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