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A systematic review and meta-analysis of otorhinolaryngological manifestations of coronavirus disease 2019 in paediatric patients

Part of: JLO Coronavirus Collection

Published online by Cambridge University Press:  17 February 2022

M Yadav ,
A Singh Open the ORCID record for A Singh [Opens in a new window] ,
J Meena  and
J M Sankar
M Yadav
Affiliation:
Department of Paediatrics, Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital, New Delhi, India
A Singh*
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, New Delhi, India
J Meena
Affiliation:
Department of Paediatric Nephrology Unit, Advanced Paediatrics Centre, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
J M Sankar
Affiliation:
Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India
*
Author for correspondence: Dr Anup Singh, room no. 4057, ENT Office, 4th floor, Teaching Block, All India Institute of Medical Sciences, Ansari Nagar, New Delhi110029, India E-mail: anoop.aiims1@gmail.com
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Abstract

Background

This meta-analysis provides a quantitative measure of the otorhinolaryngological manifestations of coronavirus disease 2019 in children.

Methods

A structured literature review was carried out using PubMed, Embase and Cochrane Central, employing pertinent search terms. The statistical analysis was performed using Stata version 14.2 software, and the analysed data were expressed as the pooled prevalence of the symptoms with 95 per cent confidence intervals.

Results

The commonest symptoms noted were cough (38 per cent (95 per cent confidence interval = 33–42; I2 = 97.5 per cent)), sore throat (12 per cent (95 per cent confidence interval =10–14; I2 = 93.7 per cent)), and nasal discharge (15 per cent (95 per cent confidence interval = 12–19; I2 = 96.9 per cent)). Anosmia and taste disturbances showed a pooled prevalence of 8 per cent each. Hearing loss, vertigo and hoarseness were rarely reported.

Conclusion

Cough, sore throat and nasal discharge were the commonest otorhinolaryngological symptoms in paediatric patients with coronavirus disease 2019. Compared with adults, anosmia and taste disturbances were infrequently reported in children.

Keywords

COVID-19ChildPrevalenceRespiratory SystemCoughOlfaction Disorders
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 7 , July 2022 , pp. 588 - 603
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Dr A Singh takes responsibility for the integrity of the content of the paper

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