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Salivary duct carcinoma of submandibular gland with trigeminal nerve invasion to intracranium

Published online by Cambridge University Press:  08 March 2006

Chia-Hug Li
Affiliation:
Department of Otolaryngology, Chang Gung University, Chang Gung Memorial Hospital in Kaohsiung, Taiwan.
Chih-Ying Su
Affiliation:
Department of Otolaryngology, Chang Gung University, Chang Gung Memorial Hospital in Kaohsiung, Taiwan.
Chih-Yen Chien
Affiliation:
Department of Otolaryngology, Chang Gung University, Chang Gung Memorial Hospital in Kaohsiung, Taiwan.
Chung-Feng Hwang
Affiliation:
Department of Otolaryngology, Chang Gung University, Chang Gung Memorial Hospital in Kaohsiung, Taiwan.
Hsiu-Yu Huang
Affiliation:
Department of Pathology, Chang Gung University, Chang Gung Memorial Hospital in KaohsiungTaiwan.

Abstract

Salivary duct carcinoma is a rare and invasive malignant tumour with rapid distant metastasis and dismal prognosis. Clinically, perineural invasion of the salivary duct carcinoma is commonly noted. Here, we present a case of salivary duct carcinoma of submandibular gland origin with perineural invasion of the trigeminal nerve proximal to the intracranium, that was well demonstrated by a magnetic resonance image (MRI) and was consistent with the clinical presentation. This case received radical resection and radiotherapy with inclusion of the skull base within the field. There was no tumour recurrence and distant metastasis 24 months post-operatively.

Type
Research Article
Copyright
© Royal Society of Medicine Press Limited 2003

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