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The relationship between haematological indices, serum gamma-glutamyl transferase and glutamate dehydrogenase, visual hepatic damage and worm burden in cattle infected with Fasciola gigantica

Published online by Cambridge University Press:  12 April 2024

E.C. Molina ,
S.P. Lozano  and
A.P. Barraca
E.C. Molina*
Affiliation:
College of Veterinary Medicine, University of Southern Mindanao, Kabacan, Cotabato 9407, Philippines
S.P. Lozano
Affiliation:
College of Veterinary Medicine, University of Southern Mindanao, Kabacan, Cotabato 9407, Philippines
A.P. Barraca
Affiliation:
College of Veterinary Medicine, University of Southern Mindanao, Kabacan, Cotabato 9407, Philippines
*
*Fax: 63 64 248 2250 E-mail: elizabeth.molina@jcu.edu.au
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Abstract

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The association between visual hepatic damage, burden of Fasciola gigantica, serum levels of gamma glutamyl transferase (GGT) and glutamate dehydrogenase (GLDH) is described from an abattoir study of 70 cattle in the Philippines. In another abattoir study of 60 cattle, the relationship between burden of F. gigantica and haematological indices was investigated. The degree of visual hepatic damage and burden of F. gigantica were significantly positively related to levels of GGT and GLDH. Red blood cell counts and packed cell volume were significantly inversely related to worm burden, but animals compensated for reduced numbers of red blood cells by increasing red cell haemoglobin content.

Type
Research Article
Information
Journal of Helminthology , Volume 80 , Issue 3 , September 2006 , pp. 277 - 279
Copyright
Copyright © Cambridge University Press 2006

References

Behm, C.A. & Sangster, N.C. (1999) Pathology, pathophysiology and clinical aspects. pp. 185–217 in Dalton, J.P. (Ed.) Fasciolosis. Wallingford, Oxon, CAB International.Google Scholar
Coles, E.H. (1986) Veterinary clinical pathology 4th edn. Philadelphia, W.B. Saunders.Google Scholar
El Samani, F., Mahmoud, O.M., Fawi, M.T., Gameel, A.A. & Haroun, E.M. (1985) Serum enzyme activity and bilirubin concentration in sheep experimentally infected with Fasciola gigantica . Journal of Comparative Pathology 95, 499–503.CrossRefGoogle ScholarPubMed
Ferre, I., Ortega-Mora, L.M. & Rojo-Vazquez, F.A. (1997) Serum and bile antibody responses (IgG and IgA) during subclinical Fasciola hepatica infection in sheep. Veterinary Parasitology 68, 261–267.CrossRefGoogle ScholarPubMed
Galtier, P., Larrieu, G., Tufenkji, A.E. & Franc, M. (1986) Incidence of experimental fasciolosis on the activity of drug-metabolizing enzymes in lamb liver. Drug Metabolism and Disposal 14, 137–141.Google ScholarPubMed
Haroun, E.M. & Hussein, M.F. (1976) Some clinico-pathological aspects of experimental Fasciola gigantica infection in calves. Journal of Helminthology 50, 29–30.CrossRefGoogle ScholarPubMed
Ogunrinade, A.F. & Bamgboye, E.A. (1980) Bovine fascioliasis in Nigeria. I. Haematological indices and their correlation with worm burden in chronic fascioliasis. British Veterinary Journal 136, 457–462.CrossRefGoogle ScholarPubMed
Roberts, J.A., Estuningsih, E., Wiedosari, E. & Spithill, T.W. (1997) Acquisition of resistance against Fasciola gigantica by Indonesian thin tail sheep. Veterinary Parasitology 73, 215–224.CrossRefGoogle ScholarPubMed
Sewell, M.M., Hammond, J.A. & Dinning, D.C. (1968) Studies on the aetiology of anaemia in chronic fascioliasis in sheep. British Veterinary Journal 124, 160–170.CrossRefGoogle ScholarPubMed
Sinclair, K.B. (1962) Observations on the clinical pathology of ovine fascioliasis. British Veterinary Journal 118, 37–53.10.1016/S0007-1935(17)43201-5CrossRefGoogle Scholar
Suhardono, , Widjajanti, S., Stevenson, P. & Carmichael, I.H. (1991) Control of Fasciola gigantica with triclabendazole in Indonesian cattle. Tropical Animal Health and Production 23, 217–220.CrossRefGoogle ScholarPubMed
Sykes, A.R., Coop, R.L. & Robinson, M.G. (1980) Chronic subclinical ovine fasciolosis: plasma glutamate dehydrogenase, gamma-glutamyl transpeptidase and aspartate aminotransferase activities and their significance as diagnostic aids. Research in Veterinary Science 28, 71–75.CrossRefGoogle ScholarPubMed
Taimur, M., Halder, A., Chowdhury, S., Akhter, N., Islam, M., Kamal, A. & Islam, K. (1993) Hematological studies on cattle exposed to Fasciola gigantica infestation. Asian-Australasian Journal of Animal Science 6, 301–303.CrossRefGoogle Scholar
Yadav, S.C., Sharma, R.L., Kalicharan, A., Mehra, U.R., Dass, R.S. & Verma, A.K. (1999) Primary experimental infection of riverine buffaloes with Fasciola gigantica . Veterinary Parasitology 82, 285–296.10.1016/S0304-4017(99)00005-9CrossRefGoogle ScholarPubMed
Yang, Q., Mao, W.H., Ferre, I., Bayon, J.E., Mao, X.Z. & Gonzalez-Gallego, J. (1998) Plasma aspartate aminotransferase (AST), glutamate dehydrogenase (GLDH) and gamma-glutamyl transpeptidase (GGT) activities in water buffaloes with experimental subclinical fasciolosis. Veterinary Parasitology 78, 129–136.10.1016/S0304-4017(98)00134-4CrossRefGoogle ScholarPubMed