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43017 Learning about Adaptive Capacity and Preparedness of CTSA Hubs

Published online by Cambridge University Press:  30 March 2021

Boris Volkov
Affiliation:
University of Minnesota Clinical and Translational Science Institute
Bart Ragon
Affiliation:
Integrated Translational Health Research Institute of Virginia
Jamie Doyle
Affiliation:
National Center for Advancing Translational Sciences, National Institutes of Health
Miriam A. Bredella
Affiliation:
Massachusetts General Hospital and Harvard Medical School
Sandra Burks
Affiliation:
University of Virginia, Integrated Translational Health Research Institute of Virginia
Gaurav Dave
Affiliation:
North Carolina Translational & Clinical Sciences Institute
Keith Herzog
Affiliation:
Northwestern University Clinical and Translational Sciences Institute
Kristi Holmes
Affiliation:
Northwestern University Clinical and Translational Sciences Institute
Veronica Hoyo
Affiliation:
University of California, San Diego Clinical and Translational Research Institute
Joe Hunt
Affiliation:
Indiana University Clinical and Translational Sciences Institute
Cathleen Kane
Affiliation:
NYU Langone’s Clinical and Translational Science Institute
Wayne T. McCormack
Affiliation:
North Carolina Translational & Clinical Sciences Institute
Tanha Patel
Affiliation:
University of Minnesota Clinical and Translational Science Institute
Chris Pulley
Affiliation:
University of Florida Clinical and Translational Science Institute
Anne Seymour
Affiliation:
Johns Hopkins University ICTR
Raj C. Shah
Affiliation:
Rush University, Institute for Translational Medicine
Laura Viera
Affiliation:
University of North Carolina at Chapel Hill, Translational & Clinical Sciences Institute
Anita Walden
Affiliation:
Oregon Clinical and Translational Research Institute
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Abstract

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ABSTRACT IMPACT: This work will inform the ongoing development of adaptive capacity and preparedness of the CTSA Program and other clinical and translational research organizations in their quest of improving processes that drive outcomes and impacts, shaping effective programs and services, and strengthening their emergency readiness and sustainability. OBJECTIVES/GOALS: -Share the progress and preliminary findings of an ‘Adaptive Capacity and Preparedness of CTSA Hubs’ CTSA Working Group; -Improve our awareness and understanding of the efficient and effective changes helping CTSA hubs build robust capacity to address METHODS/STUDY POPULATION: A multi-case study including: - Triangulating multiple sources of information and mixed methods (survey/interviews of research administrators, researchers, evaluators, and other key stakeholders), literature review, document and M&E system information analysis, and expert review; - Describing CTSA hubs’ experiences as related to research implementation, translation, and support during the time of emergency; - Administering a comprehensive survey of the CTSAs addressing their challenges, lessons learned, and practices that work in various program components/areas. Data collection includes aggregate and cross-sectional data, with representation based on CTSA size, maturity, and population density. RESULTS/ANTICIPATED RESULTS: The described approach shows sound promise to investigate and share strategies and best practices for building adaptive capacity and preparedness of CTSAs -- across various scientific sectors, translational research spectrum, and the goals outlined by NCATS for the CTSA program. The anticipated results of this research will include the identified/shared innovative solutions and lessons learned for this rapidly emerging, high-priority clinical and translational science issue. ‘High-quality lessons learned’ are those that represent principles extrapolated from multiple sources and triangulated to increase transferability to new contexts and situations. DISCUSSION/SIGNIFICANCE OF FINDINGS: The project provides useful knowledge and tools to research organizations and stakeholders across multiple disciplines -- for mitigating the impact of the COVID-19 disaster via effective adjusting programs, practices, and processes, and building capacity for future successful, ‘emergency ready and responsive’ research and training.

Type
Evaluation
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Association for Clinical and Translational Science 2021