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3128 Copula-Based Regression Models for Correlated Bivariate Binary Outcomes: Application to Ophthalmologic Data Structures

Published online by Cambridge University Press:  26 March 2019

Haifa Alqahtani
Affiliation:
Georgetown - Howard Universities
John Kwagyan
Affiliation:
Georgetown - Howard Universities
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Abstract

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OBJECTIVES/SPECIFIC AIMS: To account for association between the pair of binary outcomes, we adopt the Clayton and Frank copulas to indirectly specify their joint distributions. METHODS/STUDY POPULATION: We propose a regression model for the joint modelling of correlated bivariate outcomes using copulas. RESULTS/ANTICIPATED RESULTS: develop full maximum likelihood inference.

Type
Basic/Translational Science/Team Science
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-ncnd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Copyright
© The Association for Clinical and Translational Science 2019