Hostname: page-component-7479d7b7d-jwnkl Total loading time: 0 Render date: 2024-07-12T09:18:32.626Z Has data issue: false hasContentIssue false

Methadone and its effect on QTc prolongation

Published online by Cambridge University Press:  13 June 2014

Deirdre Hussey
Affiliation:
National Drug Treatment Centre, Pearse Street, Dublin, Ireland
Catherine McCarthy
Affiliation:
National Drug Treatment Centre, Pearse Street, Dublin, Ireland
Eamon Keenan
Affiliation:
National Drug Treatment Centre, Pearse Street, Dublin, Ireland
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Letters to Editor
Copyright
Copyright © Cambridge University Press 2009

References

1.Wesohules, DJ, McMath, JA, Gallagher, Ret al.Methadone and the hospice patient: prescribing trends in the home-care setting. Pain Med 2003; 4: 269–76.CrossRefGoogle Scholar
2.Niveau, G, Rougemont, AL, La Harpe, R. Methadone Maintenance treatment, criminality and overdose – related deaths. An ecological study, 1983 – 1999. Eur J Public Health 2002; 12: 224–7.CrossRefGoogle ScholarPubMed
3.McCaffrey, BR. Methadone treatment: our vision for the future. J Addict Dis. 2001; 20:93101Google Scholar
4.Stitcherling, C, Schaer, B, Ammann, Pet al, Methadone-induced Torsades de Pointes tachycardias. Swiss Med Weekly 2005 135: 282285.Google Scholar
5.European Agency for the evaluation of Medicinal Products, EMEA public statement to suspend the marketing authorization for Orlaam (levacetylmethadol) in the European Union. 04 19 2001.Google Scholar
6.Deamer, RL, Nllson, DR, Clark, DSet al.Torsades de Pointes associated with high dose levomethadyl acetate (ORLAAM) J Addict Dos 2001; 20: 714CrossRefGoogle ScholarPubMed
Stitcherling, C, Schaer, B, Ammann, Pet al, Methadone -induced Torsades de Pointes tachycardias. Swiss Med Weekly 2005 135: 282285.Google Scholar
7.Gupta, A, Lawrence, A, Krishnan, Ket al, Current Concepts in the mechanism and management of drug-induced QT prolongation and Torsades de Pointes. American Heart Journal, 06 2007 153(6): 891899.CrossRefGoogle Scholar
8.Martell, BAet al, Impact of methadone treatment on cardiac repolarisation and conduction in opioid users. Am J cardiol 2005; 95: 915918CrossRefGoogle Scholar
9.Krantz, MJ, Lewkowiez, L, Hays, Het al.Torsades depointes associated with very high dose methadone. Ann Intern Med 2002; 137: 501–4CrossRefGoogle Scholar
10.Whret, G, Voide, C, Gex-Fabry, Met al.Drug Induced Long QT Syndrome in Injection drug users receiving Methadone. Arch Intern Med 2006:166: 12801287Google Scholar
11.Fanoe, S, Huidt, C, Ege, Pet al, Syncope and QT prolongation among patients treated with methadone for heroin dependence in the City of Copenhagen. Heart 2007 09; 93(9) 1051–5CrossRefGoogle ScholarPubMed
12.Lamont, P, Hunt, S, A twist on Torsade: A Prolonged QT interval on Methadone. J Gen Intern Med 206, 11 21 (11), C9C12CrossRefGoogle Scholar