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Reintroduction of antipsychotics in a patient with clozapine induced neuroleptic malignant syndrome
Published online by Cambridge University Press: 13 June 2014
Abstract
We report a case of neuroleptic malignant syndrome (NMS) secondary to clozapine treatment in which re-introduction of two different antipsychotics led to elevation of creatinine kinase (CK) levels without associated symptoms of NMS. The significance of CK levels as a marker for NM S is discussed in the light of previous findings in this area. We suggest clinical guidelines for antipsychotic rechallenge after the occurrence of NMS.
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