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Borderline personality disorder and clozapine

Published online by Cambridge University Press:  13 June 2014

Emer Rutledge
Affiliation:
Central Mental Hospital, Dundrum, Dublin 14, Ireland
Mary O'Regan
Affiliation:
Central Mental Hospital, Dundrum, Dublin 14, Ireland
Damian Mohan
Affiliation:
Central Mental Hospital, Dundrum, Dublin 14, Ireland

Abstract

Clozapine is an atypical anti-psychotic medication that has proved useful in the management of both psychotic and mood disorders and that has been shown to decrease aggression and the risk of suicide, which suggests that clozapine may be useful in the management of severe borderline personality disorder. Here we present the case of a 36 year old female with severe borderline personality disorder with symptoms of psychosis, aggression and violence. We discuss how treatment with clozapine resulted in a marked clinical improvement in this patient.

Type
Case Report
Copyright
Copyright © Cambridge University Press 2007

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References

1.Binks, CA., Fenton, M., Pharmacological interventions for People with Borderline personality Disorder (Review). Cochrane Collaboration 2006.Google Scholar
2.Linehan, M.M., Cognitive Behavioural Treatment of Borderline Personality Disorder. New York, NY: Guilford Press 1993a.Google Scholar
3. DSM-IV, APA.Google Scholar
4.Swinton, M., Clozapine in severe borderline personality disorder. The Journal of Forensic Psychiatry 2001; Vol 12 No 3580591.CrossRefGoogle Scholar
5.Grootens, K.P., Verkes, R.J., Emerging Evidence for the use of Atypical Antipsychotics in Borderline Personality Disorder. Pharmacopsychiatry 2005; 38: 2023.CrossRefGoogle ScholarPubMed
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