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A normative study of total scores of the CERAD neuropsychological assessment battery in an educationally diverse elderly population

Published online by Cambridge University Press:  30 July 2014

Ji Young Han
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
Eun Hyun Seo
Affiliation:
Division of Natural Medical Sciences, College of Health Science, Chosun University, Gwangju, South Korea
Dahyun Yi
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
Bo Kyung Sohn
Affiliation:
Department of Neuropsychaitry, Boramae Medical Center, Seoul, South Korea
Young Min Choe
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
Min Soo Byun
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
Hyo Jung Choi
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
Shin Gyeom Kim
Affiliation:
Department of Neuropsychiatry, Soonchunhyang University Bucheonhospital, Bucheon, South Korea
Shin Young Park
Affiliation:
Department of Neuropsychiatry, Daelim Saint Mary's Hospital, Seoul, South Korea
Jee Wook Kim
Affiliation:
Department of Neuropsychiatry, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, South Korea
Jong Chul Youn
Affiliation:
Department of Neuropsychiatry, Gyeonggi Provincial Hospital for the Elderly, Yongin, South Korea
Jin Hyeong Jhoo
Affiliation:
Department of Psychiatry, Kangwon National University Hospital, Chunchon, South Korea
Jung Hie Lee
Affiliation:
Department of Psychiatry, Kangwon National University Hospital, Chunchon, South Korea
Ki Woong Kim
Affiliation:
Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, South Korea
Jong Inn Woo
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
Dong Young Lee*
Affiliation:
Department of Neuropsychiatry, Seoul National University Hospital, Seoul, South Korea
*
Correspondence should be addressed to: Dr Dong Young Lee, MD, Ph.D., Department of Neuropsychiatry, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea. Phone: +82.2-2072-2205; Fax: +82.2-744-7241. Email: selfpsy@snu.ac.kr.

Abstract

Background:

This study aimed to investigate the influences of age, education, and gender on the two total scores (TS-I and TS-II) of the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological assessment battery (CERAD-NP) and to provide normative information based on an analysis for a large number of elderly persons with a wide range of educational levels.

Methods:

In the study, 1,987 community-dwelling healthy volunteers (620 males and 1,367 females; 50–90 years of age; and zero to 25 years of education) were included. People with serious neurological, medical, and psychiatric disorders (including dementia) were excluded. All participants underwent the CERAD-NP assessment. TS-I was generated by summing raw scores from the CERAD-NP subtests, excluding Mini-Mental State Examination and Constructional Praxis (CP) recall subtests. TS-II was calculated by adding CP recall score to TS-I.

Results:

Both TS-I and TS-II were significantly influenced by demographic variables. Education accounted for the greatest proportion of score variance. Interaction effect between age and gender was found. Based on the results obtained, normative data of the CERAD-NP total scores were stratified by age (six overlapping tables), education (four strata), and gender.

Conclusions:

The normative information will be very useful for better interpretation of the CERAD-NP total scores in various clinical and research settings and for comparing individuals’ performance of the battery across countries.

Type
Research Article
Copyright
Copyright © International Psychogeriatric Association 2014 

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