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USING THE INTEGRATE-HTA GUIDANCE: EXPERIENCE FROM CADTH

Published online by Cambridge University Press:  16 November 2017

Ken Bond
Affiliation:
Canadian Agency for Drugs and Technologies in Healthkenb@cadth.ca
Laura Weeks
Affiliation:
Canadian Agency for Drugs and Technologies in Health

Abstract

Objectives: The aim of this study was to describe an initial exploration by CADTH, Canada's pan-Canadian health technology assessment (HTA) agency, in using the INTEGRATE-HTA guidance in the production of an HTA that examined the use of both in-center and in-home dialysis modalities for the treatment of end-stage kidney disease in adults in Canada.

Methods and Results: We outline CADTH's standard HTA production process and context and then describe the experience of the assessment team in using the INTEGRATE-HTA guidance, specifically to help structure and guide the use of a logic model, the identification of implementation issues, and the identification and examination of ethical issues. For each of the aspects, we describe and reflect on how the assessment team used the guidance, challenges that were encountered in its use, and whether and how we might address these challenges when using the INTEGRATE-HTA guidance in the future.

Conclusions: INTEGRATE-HTA provided detailed and helpful guidance for truly integrating wide-ranging aspects of HTA. Our agency was challenged by a steep learning curve for assessment team members, tight project timelines, and a misalignment of current HTA processes with those required to implement the guidance. Nevertheless, using the guidance initiated a dialogue about what might be needed to assess complex interventions and the potential process changes that could facilitate conducting more integrated assessments.

Type
Theme Submissions
Copyright
Copyright © Cambridge University Press 2017 

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References

REFERENCES

1. Whalster, P, Brereton, L, Burns, J, et al. Guidance on the integrated assessment of complex health technologies—The INTEGRATE-HTA Model. 2016. Available: http://www.integrate-hta.eu/downloads/ Google Scholar
2. Introduction to INTEGRATE HTA and Agency Experiences. INAHTA webinar. https://www.youtube.com/watch?v=2s5oPiwzZiw&feature=player_embedded. (accessed October 4, 2016).Google Scholar
3. Rowhwer, A, Booth, A, Pfadenhauer, L, et al. Guidance on the use of logic models in health technology assessments of complex interventions. 2016. http://www.integrate-hta.eu/downloads/.Google Scholar
4. Lysdahl, KB, Mozygemba, K, Burns, J, Chilcott, JB, Bronneke, JB, Hofmann, B (eds). Guidance for assessing effectiveness, economic aspects, ethical aspects, socio-cultural aspects and legal aspects in complex technologies. 2016. http://www.integrate-hta.eu/downloads/ Google Scholar
5. Pfadenhauer, L, Rohwer, A, Burns, J, et al. Guidance for the assessment of context and implementation in health technology assessment (HTA) and systematic reviews of complex interventions: The context and implementation of complex interventions (CICI) framework. 2016. http://www.integrate-hta.eu/downloads/ Google Scholar
6. HTERP Deliberative Framework (May 2015). https://www.cadth.ca/sites/default/files/pdf/hterp/HTERP_DFW_e.pdf (accessed November 15, 2016)Google Scholar
7. CADTH. Dialysis modalities for the treatment of end-stage kidney disease: a health technology assessment - project protocol. Ottawa: CADTH; 2016 Jun. (CADTH optimal use report; vol. 6, no. 2a). https://www.cadth.ca/dv/dialysis-modalities-treatment-end-stage-kidney-disease-project-protocol (accessed October 5, 2017).Google Scholar