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EARLY ASSESSMENT AND PREDICTION OF POTENTIAL IMPACT OF THE IMPLANTATION OF POLYURETHANE SCAFFOLD IN PARTIAL MENISCAL LESIONS: A PILOT HORIZON SCANNING ACTIVITY IN SOUTH KOREA

Published online by Cambridge University Press:  18 December 2015

Ji Yun Tark
Affiliation:
Department of Horizon Scanning for Innovative Global Health Technology, National Evidence-Based Healthcare Collaborating Agency (NECA)
Ji-young Jeong
Affiliation:
Division for New Health Technology Assessment, National Evidence-Based Healthcare Collaborating Agency (NECA)
Min Lee
Affiliation:
Division for New Health Technology Assessment, National Evidence-Based Healthcare Collaborating Agency (NECA)
Eunjung Park
Affiliation:
Department of Horizon Scanning for Innovative Global Health Technology, National Evidence-Based Healthcare Collaborating Agency (NECA)
Jooyeon Park
Affiliation:
Department of Horizon Scanning for Innovative Global Health Technology, National Evidence-Based Healthcare Collaborating Agency (NECA)
Ji Jeong Park
Affiliation:
Department of Horizon Scanning for Innovative Global Health Technology, National Evidence-Based Healthcare Collaborating Agency (NECA)
Sungkyu Lee
Affiliation:
Department of Horizon Scanning for Innovative Global Health Technology, National Evidence-Based Healthcare Collaborating Agency (NECA)
Chaemin Shin
Affiliation:
Department of Horizon Scanning for Innovative Global Health Technology, National Evidence-Based Healthcare Collaborating Agency (NECA) blu0924@neca.re.kr
Corresponding
E-mail address:

Abstract

Objectives: The aim of this study was to predict the potential impact of the introduction of implantation of polyurethane scaffold for the treatment of partial meniscal lesions in the South Korean healthcare system.

Methods: The horizon scanning process was used to select a target technology and assess its potential impacts on patients and the Korean healthcare system. We identified and filtered research-phase health technologies that are not listed yet in Korean, but appear promising. After a process of prioritization, we chose the implantation of polyurethane scaffolds as a target technology. Then, through the procedures of assessment and peer review, we analyzed current evidence and its predicted potential impacts.

Results: There were eight studies included in the review: one prospective cohort and seven case-series studies. Six revealed significant improvements in function and pain relief. Of the six studies, which reported safety endpoints, four stated no major postoperative complications related to scaffold, and two reported adverse events and serious adverse events such as pain, joint swelling, et cetera. We also included the potential impact of this technology based on the experts’ consultation. They all agreed that it would satisfy the diverse needs of patients and fulfill clinical needs. However, the majority of related clinical studies were based on short-term follow-up observations without any validation process involving comparison with control groups.

Conclusions: Through a horizon scanning activity, we found that the implantation of polyurethane scaffolds is a promising technology to resolve articular cartilage defects; however, long-term evidence with comparison groups for safety and effectiveness is required.

Type
Assessments
Copyright
Copyright © Cambridge University Press 2015 

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References

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EARLY ASSESSMENT AND PREDICTION OF POTENTIAL IMPACT OF THE IMPLANTATION OF POLYURETHANE SCAFFOLD IN PARTIAL MENISCAL LESIONS: A PILOT HORIZON SCANNING ACTIVITY IN SOUTH KOREA
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EARLY ASSESSMENT AND PREDICTION OF POTENTIAL IMPACT OF THE IMPLANTATION OF POLYURETHANE SCAFFOLD IN PARTIAL MENISCAL LESIONS: A PILOT HORIZON SCANNING ACTIVITY IN SOUTH KOREA
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EARLY ASSESSMENT AND PREDICTION OF POTENTIAL IMPACT OF THE IMPLANTATION OF POLYURETHANE SCAFFOLD IN PARTIAL MENISCAL LESIONS: A PILOT HORIZON SCANNING ACTIVITY IN SOUTH KOREA
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