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Risk Factors for Infection with Escherichia coli in Nursing Home Residents Colonized with Fluoroquinolone-Resistant E. coli

Published online by Cambridge University Press:  23 January 2015

Sara Manning
Affiliation:
Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Ebbing Lautenbach
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Pam Tolomeo
Affiliation:
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania
Jennifer H. Han*
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
*
Address correspondence to Jennifer Han, MD, MSCE, Division of Infectious Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 811 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 (jennifer.han@uphs.upenn.edu).

Abstract

A case-control study to determine risk factors for clinical infection with Escherichia coli was conducted among nursing home residents colonized with fluoroquinolone-resistant E. coli. Among 94 subjects, 11 (12%) developed infections with E. coli. Risk factors included the presence of a urinary catheter or tracheostomy, diabetes mellitus, and trimethoprim-sulfamethoxazole exposure.

Infect Control Hosp Epidemiol 2015;00(0): 1–3

Type
Concise Communications
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

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References

REFERENCES

1. Vromen, M, van der Ven, AJ, Knols, A, Stobberingh, EE. Antimicrobial resistance patterns in urinary isolates from nursing home residents. Fifteen years of data reviewed. J Antimicrob Chemother 1999;44:113116.Google Scholar
2. Viray, M, Linkin, D, Maslow, JN, et al. Longitudinal trends in antimicrobial susceptibilities across long-term-care facilities: emergence of fluoroquinolone resistance. Infect Control Hosp Epidemiol 2005;26:5662.Google Scholar
3. Han, JH, Maslow, J, Han, X, et al. Risk factors for the development of gastrointestinal colonization with fluoroquinolone-resistant Escherichia coli in residents of long-term care facilities. J Infect Dis 2014;209:420425.Google Scholar
4. Stone, ND, Ashraf, MS, Calder, J, et al.; Society for Healthcare Epidemiology Long-Term Care Special Interest Group. Surveillance definitions of infections in long-term care facilities: revisiting the McGeer criteria. Infect Control Hosp Epidemiol 2012;33:965977.Google Scholar
5. Nicolle, LE, Bentley, DW, Garibaldi, R, Neuhaus, EG, Smith, PW. Antimicrobial use in long-term–care facilities. Infect Control Hosp Epidemiol 2000;21:537545.Google Scholar
6. Das, R, Perrelli, E, Towle, V, Van Ness, PH, Juthani-Mehta, M. Antimicrobial susceptibility of bacteria isolated from urine samples obtained from nursing home residents. Infect Control Hosp Epidemiol 2009;30:11161119.Google Scholar
7. Nicolle, LE. The chronic indwelling catheter and urinary infection in long-term–care facility residents. Infect Control Hosp Epidemiol 2001;22:316321.Google Scholar
8. Wang, L, Lansing, B, Symons, K, et al. Infection rate and colonization with antibiotic-resistant organisms in skilled nursing facility residents with indwelling devices. Eur J Clin Microbiol Infect Dis 2012;31:17971804.Google Scholar
9. Geerlings, SE, Hoepelman, AI. Immune dysfunction in patients with diabetes mellitus (DM). FEMS Immunol Med Microbiol 1999;26:259266.Google Scholar