Hostname: page-component-8448b6f56d-dnltx Total loading time: 0 Render date: 2024-04-23T12:28:15.962Z Has data issue: false hasContentIssue false

Predicting asymptomatic severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection rates of inpatients: A time-series analysis

Published online by Cambridge University Press:  24 June 2021

Frida Rivera
Affiliation:
Division of Infectious Diseases, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin
Kwang Woo Ahn
Affiliation:
Department of Biostatistics, Medical College of Wisconsin, Milwaukee, Wisconsin
L. Silvia Munoz-Price*
Affiliation:
Division of Infectious Diseases, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin
*
Author for correspondence: L. Silvia Munoz-Price, E-mail: smunozprice@mcw.edu

Abstract

Asymptomatic SARS-CoV-2 infections are often difficult to identify because widespread surveillance has not been the norm. Using time-series analyses, we examined whether COVID-19 rates at the county level could predict positivity rates among asymptomatic patients in a large health system. Asymptomatic positivity rates at the system level and county-level COVID-19 rates were not associated.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Guan, WJ, Ni, ZY, Hu, Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382:17081720.Google ScholarPubMed
Hu, Z, Song, C, Xu, C, et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Sci China Life Sci 2020;63:706711.CrossRefGoogle ScholarPubMed
Syangtan, G, Bista, S, Dawadi, P, Rayamajhee, B, Shrestha, LB, Tuladhar, R, Joshi, DR. Asymptomatic SARS-CoV-2 carriers: a systematic review and meta-analysis. Front Public Health 2021;8:587374.CrossRefGoogle ScholarPubMed
Oran, DP, Topol, EJ. Prevalence of asymptomatic SARS-CoV-2 infection: a narrative review. Ann Intern Med 2020;173:362367.Google ScholarPubMed
Lavezzo, E, Franchin, E, Ciavarella, C, et al. Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’. Nature 2020;584:425429.CrossRefGoogle ScholarPubMed
Kumar, N, Shahul Hameed, SK, Babu, GR, et al. Descriptive epidemiology of SARS-CoV-2 infection in Karnataka state, South India: transmission dynamics of symptomatic vs asymptomatic infections. EClinicalMedicine 2021:100717.Google Scholar
Mizumoto, K, Kagaya, K, Zarebski, A, Chowell, G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill 2020;25(10):2000180.Google Scholar
Sutton, D, Fuchs, K, D’Alton, M, Goffman, D. Universal screening for SARS-CoV-2 in women admitted for delivery. N Engl J Med 2020;382:21632164.CrossRefGoogle ScholarPubMed
Goldfarb, IT, Diouf, K, Barth, WH, et al. Universal SARS-CoV-2 testing on admission to the labor and delivery unit: low prevalence among asymptomatic obstetric patients. Infect Control Hosp Epidemiol 2020;41:10951096.Google Scholar
Rivera, F, Safdar, N, Ledeboer, N, Schaack, G, Chen, DJ, Munoz-Price, LS. Prevalence of SARS-CoV-2 asymptomatic infections in two large academic health systems in Wisconsin. Clin Infect Dis 2020:ciaa1225.Google Scholar
COVID-19: Wisconsin Cases. Wisconsin Department of Health Services. https://www.dhs.wisconsin.gov/covid-19/cases.htm. Published 2020. Accessed December 10, 2020.Google Scholar
Area deprivation index. Neighborhood Atlas website. https://www.neighborhoodatlas.medicine.wisc.edu/mapping. Accessed June 23, 2020.Google Scholar
Supplementary material: File

Rivera et al. supplementary material

Rivera et al. supplementary material 1

Download Rivera et al. supplementary material(File)
File 12.5 KB
Supplementary material: Image

Rivera et al. supplementary material

Rivera et al. supplementary material 2

Download Rivera et al. supplementary material(Image)
Image 4.7 MB